William Gross, MD, PhD

Assistant Professor

Contact Information

bgross@mcw.edu

                
                    Research Areas of Interest
                
                    Electrocorticography
Language
Machine Learning
Magnetic Resonance Imaging

                    Research Experience
                
                    Intraoperative Neurophysiological Monitoring
Magnetic Resonance Imaging
Neurosurgery

                    Clinical Expertise
                
                    Anesthesiology

                    Methodologies and Techniques
                
                    Electrocorticography
Electroencephalography
Magnetic Resonance Imaging
Magnetoencephalography

                    Leadership Positions
                
                    Medical Student Anesthesiology Clerkship Director

Research Interests

Dr. Gross’s research is focused on understanding the neural underpinnings of our language system and developing translational applications to patients.

Current projects include mapping the language system with fMRI to plan neurosurgical resections, exploring language networks using electrocorticography during awake craniotomies, and developing machine learning models to decode conceptual knowledge from brain activity.

Reliable change on the selective reminding test in a series of left-hemisphere language dominant patients with right temporal lobe epilepsy.

(Pillay SB, Gross WL, Janecek JK, Binder JR, Oleksy AJ, Swanson SJ.) Epilepsy Behav. 2023 Jan;138:109004 PMID: 36473300 PMCID: PMC9885384 SCOPUS ID: 2-s2.0-85143541324 12/07/2022
Late dominance of the right hemisphere during narrative comprehension.

(Youssofzadeh V, Conant L, Stout J, Ustine C, Humphries C, Gross WL, Shah-Basak P, Mathis J, Awe E, Allen L, DeYoe EA, Carlson C, Anderson CT, Maganti R, Hermann B, Nair VA, Prabhakaran V, Meyerand B, Binder JR, Raghavan M.) Neuroimage. 2022 Dec 01;264:119749 PMID: 36379420 PMCID: PMC9772156 SCOPUS ID: 2-s2.0-85141915479 11/16/2022
Semantic network activation facilitates oral word reading in chronic aphasia.

(Pillay SB, Gross WL, Heffernan J, Book DS, Binder JR.) Brain Lang. 2022 Oct;233:105164 PMID: 35933744 PMCID: PMC9948519 SCOPUS ID: 2-s2.0-85135407900 08/08/2022
Prediction of Naming Outcome With fMRI Language Lateralization in Left Temporal Epilepsy Surgery.

(Gross WL, Helfand AI, Swanson SJ, Conant LL, Humphries CJ, Raghavan M, Mueller WM, Busch RM, Allen L, Anderson CT, Carlson CE, Lowe MJ, Langfitt JT, Tivarus ME, Drane DL, Loring DW, Jacobs M, Morgan VL, Allendorfer JB, Szaflarski JP, Bonilha L, Bookheimer S, Grabowski T, Vannest J, Binder JR, FMRI in Anterior Temporal Epilepsy Surgery (FATES) Study.) Neurology. 2022 Jun 07;98(23):e2337-e2346 PMID: 35410903 PMCID: PMC9202528 SCOPUS ID: 2-s2.0-85131545635 04/13/2022
Intracranial Vascular Procedures.

(Gross WL, Sacho RH.) Anesthesiol Clin. 2021 Mar;39(1):1-18 PMID: 33563374 SCOPUS ID: 2-s2.0-85099139893 02/11/2021
Mapping language from MEG beta power modulations during auditory and visual naming.

(Youssofzadeh V, Stout J, Ustine C, Gross WL, Conant LL, Humphries CJ, Binder JR, Raghavan M.) Neuroimage. 2020 Oct 15;220:117090 PMID: 32593799 SCOPUS ID: 2-s2.0-85086940876 07/01/2020
Temporal lobe regions essential for preserved picture naming after left temporal epilepsy surgery.

(Binder JR, Tong JQ, Pillay SB, Conant LL, Humphries CJ, Raghavan M, Mueller WM, Busch RM, Allen L, Gross WL, Anderson CT, Carlson CE, Lowe MJ, Langfitt JT, Tivarus ME, Drane DL, Loring DW, Jacobs M, Morgan VL, Allendorfer JB, Szaflarski JP, Bonilha L, Bookheimer S, Grabowski T, Vannest J, Swanson SJ, fMRI in Anterior Temporal Epilepsy Surgery (FATES) study.) Epilepsia. 2020 Sep;61(9):1939-1948 PMID: 32780878 PMCID: PMC7722029 SCOPUS ID: 2-s2.0-85089258019 08/12/2020
Changes in description naming for common and proper nouns after left anterior temporal lobectomy.

(Swanson SJ, Conant LL, Humphries CJ, LeDoux M, Raghavan M, Mueller WM, Allen L, Gross WL, Anderson CT, Carlson CE, Busch RM, Lowe M, Tivarus ME, Drane DL, Loring DW, Jacobs M, Morgan VL, Szaflarski J, Bonilha L, Bookheimer S, Grabowski T, Phatak V, Vannest J, Binder JR, FMRI in Anterior Temporal Epilepsy Surgery (FATES) study.) Epilepsy Behav. 2020 May;106:106912 PMID: 32179500 PMCID: PMC7195239 SCOPUS ID: 2-s2.0-85081244333 03/18/2020
Propofol Sedation Alters Perceptual and Cognitive Functions in Healthy Volunteers as Revealed by Functional Magnetic Resonance Imaging.

(Gross WL, Lauer KK, Liu X, Roberts CJ, Liu S, Gollapudy S, Binder JR, Li SJ, Hudetz AG.) Anesthesiology. 2019 Aug;131(2):254-265 PMID: 31314747 PMCID: PMC6640651 SCOPUS ID: 2-s2.0-85077347748 07/18/2019
Regional entropy of functional imaging signals varies differently in sensory and cognitive systems during propofol-modulated loss and return of behavioral responsiveness.

(Liu X, Lauer KK, Ward BD, Roberts CJ, Liu S, Gollapudy S, Rohloff R, Gross W, Xu Z, Chen S, Wang L, Yang Z, Li SJ, Binder JR, Hudetz AG.) Brain Imaging Behav. 2019 Apr;13(2):514-525 PMID: 29737490 PMCID: PMC6239968 SCOPUS ID: 2-s2.0-85046653018 05/09/2018
The Neural Basis of Successful Word Reading in Aphasia.

(Pillay SB, Gross WL, Graves WW, Humphries C, Book DS, Binder JR.) J Cogn Neurosci. 2018 Apr;30(4):514-525 PMID: 29211656 PMCID: PMC9926535 SCOPUS ID: 2-s2.0-85042764522 12/07/2017
Fine-Grained Parcellation of Brain Connectivity Improves Differentiation of States of Consciousness During Graded Propofol Sedation.

(Liu X, Lauer KK, Ward BD, Roberts CJ, Liu S, Gollapudy S, Rohloff R, Gross W, Xu Z, Chen G, Binder JR, Li SJ, Hudetz AG.) Brain Connect. 2017 Aug;7(6):373-381 PMID: 28540741 PMCID: PMC5685154 SCOPUS ID: 2-s2.0-85027416134 05/26/2017

William Gross, MD, PhD

Assistant Professor

Contact Information

Research Areas of Interest

Research Experience

Clinical Expertise

Methodologies and Techniques

Leadership Positions

Research Interests

Publications