Michael T. Zimmermann, PhD
Director, Computational Structural Genomics Unit, Linda T. and John A. Mellowes Center for Genomic Sciences and Precision Medicine
Locations
- Mellowes Center
Research Areas of Interest
- Chromatin
- Chromosomal Proteins, Non-Histone
- Gene Expression Profiling
- Genetic Predisposition to Disease
- Genetic Variation
- Genomics
- Human Genetics
- Molecular Dynamics Simulation
- Multiprotein Complexes
- Mutation
- Mutation, Missense
- Neoplasms
Leadership Positions
- Assistant Professor of Bioinformatics - Clinical and Translational Science Institute, Medical College of Wisconsin
- Director, Computational Structural Genomics Unit, Linda T. and John A. Mellowes Center for Genomic Sciences and Precision Medicine
- MCW Program and Course Director, Joint Program in Bioinformatics between Marquette University and Medical College of Wisconsin
- MCW Research Computing Center, Faculty Advisory Committee; Chair (elected, 2022-2024), Co-Chair (elected, 2020-2022), and Member (2020-Present)
- Strategic Steering Committee, Data Science Institute, Medical College of Wisconsin
- Visiting Assistant Professor – Department of Mathematics, Marquette University
Publications
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(Gong M, Li J, Qin Z, Machado Bressan Wilke MV, Liu Y, Li Q, Liu H, Liang C, Morales-Rosado JA, Cohen ASA, Hughes SS, Sullivan BR, Waddell V, van den Boogaard MH, van Jaarsveld RH, van Binsbergen E, van Gassen KL, Wang T, Hiatt SM, Amaral MD, Kelley WV, Zhao J, Feng W, Ren C, Yu Y, Boczek NJ, Ferber MJ, Lahner C, Elliott S, Ruan Y, Mignot C, Keren B, Xie H, Wang X, Popp B, Zweier C, Piard J, Coubes C, Mau-Them FT, Safraou H, Innes AM, Gauthier J, Michaud JL, Koboldt DC, Sylvie O, Willems M, Tan WH, Cogne B, Rieubland C, Braun D, McLean SD, Platzer K, Zacher P, Oppermann H, Evenepoel L, Blanc P, El Khattabi L, Haque N, Dsouza NR, Zimmermann MT, Urrutia R, Klee EW, Shen Y, Du H, Rappaport L, Liu CM, Chen X.) Am J Hum Genet. 2024 Nov 07;111(11):2392-2410 PMID: 39419027 PMCID: PMC11568763 SCOPUS ID: 2-s2.0-85207372821 10/18/2024
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(Hall WA, Mathison AJ, DeVoe E, Tschannen M, Wendt-Andrae J, Straza M, Awan M, Puckett LL, Lawton CAF, Schultz C, Urrutia R, Kerns S, Torres-Roca JF, Li XA, Erickson B, Nevalainen MT, Zimmermann MT, Paulson E.) Int J Radiat Oncol Biol Phys. 2024 Oct 01;120(2):570-578 PMID: 38819340 SCOPUS ID: 2-s2.0-85194948255 05/31/2024
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Mutant KRAS inhibitors enter the scene of precision therapeutics for pancreatic cancer.
(Pollin G, Lomberk GA, Mathison AJ, Zimmermann MT, Urrutia R.) J Gastrointest Oncol. 2024 Aug 31;15(4):1996-2001 PMID: 39279937 PMCID: PMC11399826 09/16/2024
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(Kim J, Zimmermann MT, Mathison AJ, Lomberk G, Urrutia R, Hong JC.) Ann Surg Open. 2024 Jun;5(2):e444 PMID: 38911661 PMCID: PMC11191965 06/24/2024
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Type I interferon signaling promotes radioresistance in head and neck cancer.
(Zenga J, Awan MJ, Frei A, Massey B, Bruening J, Shukla M, Sharma GP, Shreenivas A, Wong SJ, Zimmermann MT, Mathison AJ, Himburg HA.) Transl Cancer Res. 2024 May 31;13(5):2535-2543 PMID: 38881922 PMCID: PMC11170510 06/17/2024
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(Bursch KL, Goetz CJ, Jiao G, Nuñez R, Olp MD, Dhiman A, Khurana M, Zimmermann MT, Urrutia RA, Dykhuizen EC, Smith BC.) J Biol Chem. 2024 Apr;300(4):107146 PMID: 38460939 PMCID: PMC11002309 SCOPUS ID: 2-s2.0-85189184192 03/10/2024
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(Dsouza NR, Cottrell CE, Davies OMT, Tollefson MM, Frieden IJ, Basel D, Urrutia R, Drolet BA, Zimmermann MT.) Life (Basel). 2024 Feb 23;14(3) PMID: 38541623 PMCID: PMC10971029 SCOPUS ID: 2-s2.0-85193266612 03/28/2024
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Mutant KRAS inhibitors enter the scene of precision therapeutics for pancreatic cancer
(Pollin G, Lomberk GA, Mathison AJ, Zimmermann MT, Urrutia R.) Journal of Gastrointestinal Oncology. 31 August 2024;15(4):1996-2001 SCOPUS ID: 2-s2.0-85203321495 08/31/2024
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(Pollin G, Mathison AJ, de Assuncao TM, Thomas A, Zeighami A, Salmonson A, Liu H, Urrutia G, Vankayala P, Pandol SJ, Hong JC, Zimmermann MT, Iovanna J, Jin VX, Urrutia R, Lomberk G.) Front Genet. 2024;15:1412767 PMID: 38948355 PMCID: PMC11211573 SCOPUS ID: 2-s2.0-85197408751 07/01/2024
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Type I interferon signaling promotes radioresistance in head and neck cancer
(Zenga J, Awan MJ, Frei A, Massey B, Bruening J, Shukla M, Sharma GP, Shreenivas A, Wong SJ, Zimmermann MT, Mathison AJ, Himburg HA.) Translational Cancer Research. 2024;13(5):2535-2543 SCOPUS ID: 2-s2.0-85195040296 01/01/2024
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(Jorge SD, Chi YI, Mazaba JL, Haque N, Wagenknecht J, Smith BC, Volkman BF, Mathison AJ, Lomberk G, Zimmermann MT, Urrutia R.) Front Genet. 2023;14:1291307 PMID: 38090150 PMCID: PMC10715303 SCOPUS ID: 2-s2.0-85179362461 12/13/2023
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(Chi YI, Jorge SD, Jensen DR, Smith BC, Volkman BF, Mathison AJ, Lomberk G, Zimmermann MT, Urrutia R.) Comput Struct Biotechnol J. 2023;21:5249-5258 PMID: 37954151 PMCID: PMC10632586 11/13/2023