Chun Liu, PhD
Assistant Professor
Locations
- MEB M4565
Contact Information
Education
PhD, Peking University
BS, China Agricultural University
Biography
Honors and Awards
2019-2022 - American Heart Association Career Development Award
2021 - American Heart Association Scientific Session Travel Award
2021 - Stanford Cardiovascular Institute Travel Award
2016-2018 - American Heart Association Postdoctoral Fellowship
2013 - Peking University Innovation Prize, Beijing, China
Research Areas of Interest
- Cancer Survivors
- Cardiovascular Diseases
- Cell Differentiation
- Cellular Reprogramming Techniques
- CRISPR-Cas Systems
- Epigenomics
- Genomics
- Induced Pluripotent Stem Cells
- Pharmacogenetics
- Systems Biology
Research Experience
- Cell Differentiation
- Cellular Reprogramming
- CRISPR-Cas Systems
- Endothelial Cells
- Gene Expression Profiling
- Induced Pluripotent Stem Cells
- Myocytes, Cardiac
Methodologies and Techniques
- Cardiovascular Diseases
- Chromatin Immunoprecipitation
- CRISPR-Cas Systems
- High-Throughput Nucleotide Sequencing
- Induced Pluripotent Stem Cells
- Sequence Analysis, DNA
- Sequence Analysis, RNA
Research Interests
WE ARE HIRING! Dr. Liu is passionate about mentoring and cultivating the next generation of scientific minds. Opportunities abound in our lab for talented students at both the graduate and undergraduate levels, as well as postdoctoral researchers. Engage with highly innovative projects that are currently underway, focusing on the fascinating fields of stem cell research and genomics. If these areas spark your interest, please don't hesitate to reach out to Dr. Liu directly. Your future in cutting-edge scientific exploration could begin with us!
- Methodologies and Techniques
- Induced pluripotent stem cell (iPSC)/reprogramming
- Human cardiovascular differentiation (cardiomyocyte, endothelial cell, smooth muscle cell, and pericyte)
- Genome editing (CRISPR and base editing)
- CRISPRi/a screen
- Perturb-seq
- Transcriptomic/Epigenomic/Proteomic analysis
- Vascular function
- Cardiomyocyte function Mentoring and Training
Publications
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(Belbachir N, Wu Y, Shen M, Zhang SL, Zhang JZ, Liu C, Knollmann BC, Lyon GJ, Ma N, Wu JC.) Circulation. 2023 Nov 14;148(20):1598-1601 PMID: 37956223 PMCID: PMC10697282 11/13/2023
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Death-seq identifies regulators of cell death and senolytic therapies.
(Colville A, Liu JY, Rodriguez-Mateo C, Thomas S, Ishak HD, Zhou R, Klein JDD, Morgens DW, Goshayeshi A, Salvi JS, Yao D, Spees K, Dixon SJ, Liu C, Rhee JW, Lai C, Wu JC, Bassik MC, Rando TA.) Cell Metab. 2023 Oct 03;35(10):1814-1829.e6 PMID: 37699398 PMCID: PMC10597643 09/13/2023
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Protocol to generate cardiac pericytes from human induced pluripotent stem cells.
(Shen M, Zhao SR, Khokhar Y, Li L, Zhou Y, Liu C, Wu JC.) STAR Protoc. 2023 Apr 27;4(2):102256 PMID: 37119139 PMCID: PMC10173856 04/29/2023
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(Shen M, Liu C, Zhao SR, Manhas A, Sundaram L, Ameen M, Wu JC.) Circulation. 2023 Feb 07;147(6):515-518 PMID: 36745700 PMCID: PMC9909621 02/07/2023
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Impaired Human Cardiac Cell Development due to NOTCH1 Deficiency.
(Ye S, Wang C, Xu Z, Lin H, Wan X, Yu Y, Adhicary S, Zhang JZ, Zhou Y, Liu C, Alonzo M, Bi J, Ramirez-Navarro A, Deschenes I, Ma Q, Garg V, Wu JC, Zhao MT.) Circ Res. 2023 Jan 20;132(2):187-204 PMID: 36583388 PMCID: PMC9852089 12/31/2022
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Statins improve endothelial function via suppression of epigenetic-driven EndMT
(Chun Liu, Mengcheng Shen, Wilson L. W. Tan, Ian Y. Chen, Yu Liu, Xuan Yu, Huaxiao Yang, Angela Zhang, Yanxia Liu, Ming-Tao Zhao, Mohamed Ameen, Mao Zhang, Eric R. Gross, Lei S. Qi, Nazish Sayed & Joseph C. Wu.) Nature Cardiovascular Research. (2023). https://doi.org/10.1038/s44161-023-00267-1 05/08/2023
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Cardiotoxicity drug screening based on whole-panel intracellular recording.
(Yang Y, Liu A, Tsai CT, Liu C, Wu JC, Cui B.) Biosens Bioelectron. 2022 Nov 15;216:114617 PMID: 36027802 PMCID: PMC9930661 08/27/2022
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The use of new CRISPR tools in cardiovascular research and medicine.
(Nishiga M, Liu C, Qi LS, Wu JC.) Nat Rev Cardiol. 2022 Aug;19(8):505-521 PMID: 35145236 PMCID: PMC10283450 02/12/2022
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Acoustic Fabrication of Living Cardiomyocyte-based Hybrid Biorobots.
(Wang J, Soto F, Ma P, Ahmed R, Yang H, Chen S, Wang J, Liu C, Akin D, Fu K, Cao X, Chen P, Hsu EC, Soh HT, Stoyanova T, Wu JC, Demirci U.) ACS Nano. 2022 Jul 26;16(7):10219-10230 PMID: 35671037 06/08/2022
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Cannabinoid receptor 1 antagonist genistein attenuates marijuana-induced vascular inflammation.
(Wei TT, Chandy M, Nishiga M, Zhang A, Kumar KK, Thomas D, Manhas A, Rhee S, Justesen JM, Chen IY, Wo HT, Khanamiri S, Yang JY, Seidl FJ, Burns NZ, Liu C, Sayed N, Shie JJ, Yeh CF, Yang KC, Lau E, Lynch KL, Rivas M, Kobilka BK, Wu JC.) Cell. 2022 May 12;185(10):1676-1693.e23 PMID: 35489334 PMCID: PMC9400797 05/01/2022
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(Shen M, Liu C, Wu JC.) Methods Mol Biol. 2022;2429:233-246 PMID: 35507165 PMCID: PMC9667909 05/05/2022
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Editorial: Cardiomyocyte Maturation: Novel Insights for Regenerative Medicine.
(Zhang M, Qian L, Liu C, Huang GN, Tao G.) Front Cell Dev Biol. 2021;9:730622 PMID: 34409043 PMCID: PMC8365607 08/20/2021