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MSTP students in the Sahoo lab

Medical Scientist Training Program

Samantha Chou

Matched at University of Texas – Houston; Specialty: Child Neurology

Faculty Advisor

Matthew Scaglione, PhD, Biochemistry

Locations

Medical Scientist Training Program

Contact Information

schou@mcw.edu

Education

BA, Cognitive Science, University of California, Berkeley, 2012

Research Interests

Neuroscience

Research Experience

Medical College of Wisconsin, 2017-2022
Advisor: Matthew Scaglione, PhD
Project: Elucidating SRCP1's therapeutic potential in Huntington's Disease

National Institute of Mental Health, 2013-2015
Advisor: Dietmar Plenz, PhD
Project: Investigated the correlations between neuronal avalanches and working memory function in non-human primates.

University of California, Berkeley, 2011-2013
Advisor: Yang Dan, PhD
Project: Studied connections between the basal forebrain and prefrontal cortex in awake mice, manipulating behavior in visual discrimination tasks using optogenetics.

Publications

Umano A, Fang K, Qu Z, Scaglione JB, Altinok S, Treadway CJ, Wick ET, Paulakonis E, Karunanayake C, Chou S, Bardakjian TM, Gonzalez-Alegre P, Page RC, Schisler JC, Brown NG, Yan D, Scaglione KM. The molecular basis of spinocerebellar ataxia type 48 caused by a de novo mutation in the ubiquitin ligase CHIP. J Biol Chem. 2022 May;298(5):101899. doi: 10.1016/j.jbc.2022.101899. Epub 2022 Apr 7. PMID: 35398354; PMCID: PMC9097460.

Meeting Abstracts

Yu, S., Ribeiro, T. L., Meisel, C., Chou, S., Mitz, A., Saunders, R., Plenz, D. (2017). Maintained avalanche dynamics during task-induced changes of neuronal activity in nonhuman primates. Elife. 6: e27119.

S. Yu*, S. Chou, A. R. Mitz, R. Saunders, D. Plenz. Rate and size modulation of neuronal avalanches during motor and cognitive tasks in macaque monkeys. Society for Neuroscience Annual Meeting 2014. Washington, DC. November 15–19, 2014.

S. Chou, S. Yu, D. Plenz. Exploring the Functional Role of Neuronal Avalanches in Monkeys Performing Visuomotor Mapping Task. NIMH 16th Annual Scientific Training Day. February 21, 2014.

S. Seshadri, T. Bellay, S. Chou, D. Plenz. Altered neuronal avalanches at the population and cell level in a rat model of schizophrenia. Computational and Systems Neuroscience (Cosyne) 2014. Salt Lake City, UT. February 27–March 1, 2014.

General Interests

Flute, sewing, cooking, board games, hip hop dance