Medical College of Wisconsin
Medical College of Wisconsin Medical College of Wisconsin
what
Anesthesiology
Hogan, Quinn MD

Quinn Hogan, MD

Professor

Contact Information

Education

BS, Stanford University, Stanford, CA
MD, Harvard Medical School, Boston, MA
Residency, Anesthesiology, Medical College of Wisconsin
Fellowship, Pain Management, Medical College of Wisconsin

Research Experience

  • Pain
  • Rats

Research Interests

  • Somatosensory physiology
  • Pain mechanisms
  • Novel analgesic approaches

Publications

Publications of Quinn H. Hogan MD from the Faculty Collaboration Database
My laboratory focuses on identifying disrupted function of sensory neurons following injury and exploring novel therapies for pain. We employ combined physiological approaches of patch-clamp electrophysiology for identification of membrane biophysics, single unit recordings by sharp electrode in intact ganglia in vitro and in vivo to evaluate neuronal function in the absence of dissociation, teased fiber recording, and microfluorometry to characterize the cytoplasmic Ca2+ signal that follows membrane activation. These approaches are ideally suited to explore the basic mechanisms of pain. My research has also emphasized the importance of valid behavioral testing as a necessary criterion for relevant pain study, as I am aware from my clinical work of the potential for divergence between animal models and human disease. I as well as other scientists investigating pain mechanisms have come to recognize that there is a major shortfall in translation of these discoveries into therapies. Therefore, my research also explores and develops novel approaches for taking advantage of the extensive backlog of mechanistic discoveries, including targeting the sensory neuron for molecular manipulations, stem cell therapy, and electrical stimulation as treatment modalities.