Victor X. Jin, PhD
Linda T. and John A. Mellowes Endowed Chair of Bioinformatics and Data Analytics; Professor, IHE/Biostatistics
Locations
- Biostatistics
8701 Watertown Plank Rd.
HRC-H5145 (office)
Milwaukee, WI 53226
Contact Information
Research Areas of Interest
- 1) Developing genomics and computational approaches for the identification of three-dimensional (3D) chromatin interactions from the various omics-seq data.
- 2) Functionally and mechanistically characterizing the roles of epigenetic marks in cancer development and progression using novel techniques such as 3C/ChIP/RT-qPCR, 3D-FISH and CRISPR/Cas9.
- 3) Adapting/applying genome-wide omics-seq techniques in patient tissues to identify epigenetic-driven therapeutic targets and biomarkers.
Research Experience
- Dr. Jin has extensive experience in developing computational and genomics approaches for analyzing various omics-seq data, and runs a systems biology lab with a balanced dry and wet components.
Leadership Positions
- Associate Director of Bioinformatics and Systems Biology, Mellowes Center for Genomic Sciences and Precision Medicine
- Director, Bioinformatics Shared Resources
Publications
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(Zhou Y, He Z, Li T, Choppavarapu L, Hu X, Cao R, Leone GW, Kahn M, Jin VX.) Cancers (Basel). 2024 Jun 12;16(12) PMID: 38927910 PMCID: PMC11201718 SCOPUS ID: 2-s2.0-85197122887 06/27/2024
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(Pollin G, Mathison AJ, de Assuncao TM, Thomas A, Zeighami L, Salmonson A, Liu H, Urrutia G, Vankayala P, Pandol SJ, Zimmermann MT, Iovanna J, Jin VX, Urrutia R, Lomberk G.) bioRxiv. 2024 Mar 16 PMID: 38529489 PMCID: PMC10962735 03/26/2024
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(Choppavarapu L, Fang K, Liu T, Jin VX.) bioRxiv. 2024 Mar 13 PMID: 38559097 PMCID: PMC10979939 04/01/2024
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(Pollin G, Mathison AJ, de Assuncao TM, Thomas A, Zeighami A, Salmonson A, Liu H, Urrutia G, Vankayala P, Pandol SJ, Hong JC, Zimmermann MT, Iovanna J, Jin VX, Urrutia R, Lomberk G.) Front Genet. 2024;15:1412767 PMID: 38948355 PMCID: PMC11211573 SCOPUS ID: 2-s2.0-85197408751 07/01/2024
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(Chimge NO, Chen MH, Nguyen C, Zhao Y, Wu X, Gonzalez PG, Ogana H, Hurwitz S, Teo JL, Chen X, Du J, Jin V, Kim YM, Ono M, Argüello RJ, Kahn M.) Curr Mol Pharmacol. 2024;17(1):e060923220758 PMID: 37691195 09/11/2023
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(Zhou Y, Li T, He Z, Choppavarapu L, Hu X, Cao R, Leone GW, Kahn M, Jin VX.) bioRxiv. 2023 Nov 14 PMID: 38013997 PMCID: PMC10680786 11/28/2023
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An essential signaling function of cytoplasmic NELFB is independent of RNA polymerase II pausing.
(Pan H, Cheng X, Rodríguez PFG, Zhang X, Chung I, Jin VX, Li W, Hu Y, Li R.) J Biol Chem. 2023 Nov;299(11):105259 PMID: 37717699 PMCID: PMC10591015 09/18/2023
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(Zhou Y, Li T, Choppavarapu L, Jin VX.) bioRxiv. 2023 Oct 02 PMID: 37873257 PMCID: PMC10592853 10/24/2023
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(Han L, Wu Y, Fang K, Sweeney S, Roesner UK, Parrish M, Patel K, Walter T, Piermattei J, Trimboli A, Lefler J, Timmers CD, Yu XZ, Jin VX, Zimmermann MT, Mathison AJ, Urrutia R, Ostrowski MC, Leone G.) Nat Commun. 2023 Jan 03;14(1):1 PMID: 36596776 PMCID: PMC9810714 SCOPUS ID: 2-s2.0-85145429848 01/04/2023
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Cas13d knockdown of lung protease Ctsl prevents and treats SARS-CoV-2 infection.
(Cui Z, Zeng C, Huang F, Yuan F, Yan J, Zhao Y, Zhou Y, Hankey W, Jin VX, Huang J, Staats HF, Everitt JI, Sempowski GD, Wang H, Dong Y, Liu SL, Wang Q.) Nat Chem Biol. 2022 Oct;18(10):1056-1064 PMID: 35879545 PMCID: PMC10082993 07/26/2022
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(Shropshire DB, Acosta FM, Fang K, Benavides J, Sun LZ, Jin VX, Jiang JX.) Front Med (Lausanne). 2022;9:965429 PMID: 36186774 PMCID: PMC9520286 10/04/2022
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Mapping nucleosome and chromatin architectures: A survey of computational methods.
(Fang K, Wang J, Liu L, Jin VX.) Comput Struct Biotechnol J. 2022;20:3955-3962 PMID: 35950186 PMCID: PMC9340519 08/12/2022