Andreas Beyer Lab

Andreas M. Beyer, PhD
Curriculum Vitae (PDF)
Twitter: @BeyerLab
abeyer@mcw.edu
Andreas M. Beyer is a professor in the Departments of Medicine and Physiology at the Medical College of Wisconsin and the co-director of the Basic and translational research program in Cardio-Oncology.
During his training in genetics and physiology, he has gained detailed expertise in generating and evaluating novel approaches in genetics, molecular biology and physiology. In his time spent in the lab he performs experimental troubleshooting involving video microscopy, fluorescent microvascular imaging, generation of genetic rodent models, physiological evaluation of in vivo vascular function and blood pressure. With the support of this research group and important local and national collaborators, the Beyer lab is using live human tissues to address important questions in vascular biology that will lead to clinically relevant findings and drive further exploration of mechanism in rodent models. His lab hopes that clinically relevant data from human tissues will enable a detailed mechanistic understanding of disease that can then be used to develop novel therapeutics and translate both diagnostics and therapies themselves to the clinic.
Lab Projects
Current Members
Laura Norwood Toro
Research Scientist I
lnorwood@mcw.edu
Laura Norwood Toro is a Research Scientist I in the Andreas Beyer Lab. Her primary responsibility is to explore the effect of chemotherapy on cardiovascular outcomes in coronary circulation and vascular endothelium. One focus of her studies is to investigate the functions of telomerase in the nucleus versus the mitochondria. Her background is in cell biology and molecular biology.
Karen Clark, PhD
Research Scientist
kaclark@mcw.edu
Karen Clark is a research scientist working with Drs. Beyer and Kriegel to investigate biological factors that lead to disparate chemotherapy treatment outcomes in breast cancer patients of color compared to Caucasian women. She is also studying the role of mitofusin 1 in the vascular endothelium and whether overexpression is a protective factor against certain stressors. Prior to joining the team, she earned her PhD in Genetics at the University of Iowa, investigating the genetic basis of susceptibility to complex diseases in a rat model of Metabolic Syndrome. Her research interests include Precision Medicine, cancer biology, and metabolism.

Steve Hammond, PhD
Postdoctoral Researcher
Steve Hammond is a postdoctoral researcher in the Beyer lab. Prior to his start at MCW, he earned his doctorate from Kansas State University where he investigated the adverse cardiovascular consequences of 5-fluorouracil chemotherapy and modalities to alleviate their occurrence. Steve is most interested in better understanding the mitochondrial contributions to cardiovascular function in health in disease. He is currently studying the role of mitochondrial signaling in the development of anticancer therapy induced microvascular dysfunction. Specifically, his primary projects aim to elucidate the role of tumor derived circulating factors and alterations in mitochondrial calcium signaling in the development of microvascular pathology during anti-cancer treatment.
Erin Birch
Research Technologist I
ebirch@mcw.edu
Erin Birch is a research technologist in Dr. Beyer and Dr. Zhang’s labs. Erin has experience researching autoimmune diseases, chronic kidney disease, and cardiovascular disease. She is working with Dr. Beyer’s lab to provide support with several projects. Erin also contributes to the analysis of microvascular function in patients with coronary artery disease, COVID-19, and healthy patients. In her free time, Erin enjoys traveling and adventuring in the Rocky Mountains.
Lukas Brandt
Research Assistant
lbrandt@mcw.edu
Lukas Brandt is a graduate student in Dr. Beyer's lab. Prior to starting at MCW's physiology program, he received his bachelor's degree from the University of Applied Science Bingen, Germany with a major in biotechnology. He received additional training in a Molecular Biology master program at the Goethe University Frankfurt, Germany before pursuing his education in physiology at MCW. His research interests are whole organ physiology with a focus on cardiovascular pathology in response to clinical used anti-cancer therapy. Lukas aims to utilize rodent models to investigate physiological and molecular changes that lead to cardiovascular disease.
Cristhian Gutierrez Huerta
Research Assistant
cgutierrez@mcw.edu
Cristhian Gutierrez Huerta is a graduate MSTP student in the Beyer/Gutterman Lab. He graduated with a BS in Applied Mathematics and Biological Sciences from the University of California, Merced in 2018. He then completed a 2-yr post-baccalaureate research fellowship at the National Heart, Lung, and Blood Institute. In the Beyer/Gutterman group, he will begin work on identifying the role of mitochondrial fission/fusion on microvascular endothelial function and its relationship to coronary artery disease progression.
Alumni/Former Trainees
- Karima Ait-Aissa
- Daniela Didier
- Johnathan Ebben
- Alena Hanson
- Joe Hockenberry
- Bill Hughes, PhD
- Andrew D. Kadlec, PhD
- Minhi Kang
- Todd Le
- Jasmine Linn
- Janée Terwoord
- Micaela Young
Recent Publications
-
(Nishijima Y, Hader SN, Birch EC, Chen Y, Widlansky ME, Beyer AM.) Cardiovasc Res. 2025 Feb 13 PMID: 39943809 02/13/2025
-
UBR1 Promotes Sex-Dependent ACE2 Ubiquitination in Hypertension.
(Elgazzaz M, Lakkappa N, Berdasco C, Mohan UP, Nuzzo A, Restivo L, Martinez A, Scarborough A, Guidry JJ, Sriramula S, Xu J, Daoud H, Mendiola Plá MA, Bowles DE, Beyer AM, Mauvais-Jarvis F, Yue X, Filipeanu CM, Lazartigues E.) Hypertension. 2025 Jan;82(1):84-95 PMID: 39601126 PMCID: PMC11655255 SCOPUS ID: 2-s2.0-85213490001 11/27/2024
-
Impaired endothelial function contributes to cardiac dysfunction: role of mitochondrial dynamics.
(Gutierrez-Huerta CA, Quiroz-Delfi G, Faleel FDM, Beyer AM.) Am J Physiol Heart Circ Physiol. 2025 Jan 01;328(1):H29-H36 PMID: 39560973 SCOPUS ID: 2-s2.0-85212326562 11/19/2024
-
Radiation-Induced Macrovessel/Microvessel Disease.
(Abe JI, Allen BG, Beyer AM, Lewandowski D, Mapuskar KA, Subramanian V, Tamplin MR, Grumbach IM.) Arterioscler Thromb Vasc Biol. 2024 Dec;44(12):2407-2415 PMID: 39445428 PMCID: PMC11842029 SCOPUS ID: 2-s2.0-85207953419 10/24/2024
-
MICU1 and MICU2 control mitochondrial calcium signaling in the mammalian heart.
(Hasan P, Berezhnaya E, Rodríguez-Prados M, Weaver D, Bekeova C, Cartes-Saavedra B, Birch E, Beyer AM, Santos JH, Seifert EL, Elrod JW, Hajnóczky G.) Proc Natl Acad Sci U S A. 2024 Aug 27;121(35):e2402491121 PMID: 39163336 PMCID: PMC11363308 SCOPUS ID: 2-s2.0-85201851900 08/20/2024
-
Clinical Implications of COVID-19-Related Endothelial Dysfunction.
(Aljadah M, Khan N, Beyer AM, Chen Y, Blanker A, Widlansky ME.) JACC Adv. 2024 Aug;3(8):101070 PMID: 39055276 PMCID: PMC11269277 07/26/2024
-
Is the peripheral microcirculation a window into the human coronary microvasculature?
(SenthilKumar G, Hammond ST, Zirgibel Z, Cohen KE, Beyer AM, Freed JK.) J Mol Cell Cardiol. 2024 Aug;193:67-77 PMID: 38848808 PMCID: PMC11260236 SCOPUS ID: 2-s2.0-85195369481 06/08/2024
-
(Bikomeye JC, Awoyinka I, Kwarteng JL, Beyer AM, Rine S, Beyer KMM.) Heart Lung Circ. 2024 May;33(5):576-604 PMID: 38184426 PMCID: PMC11144115 SCOPUS ID: 2-s2.0-85181809389 01/07/2024
-
(Jahan J, Joshi S, Oca IM, Toelle A, Lopez-Yang C, Chacon CV, Beyer AM, Garcia CA, Jarajapu YP.) Biochem Pharmacol. 2024 Apr;222:116109 PMID: 38458330 PMCID: PMC11007670 SCOPUS ID: 2-s2.0-85187326117 03/09/2024
-
(Asulin M, Gorodetzer N, Fridman R, Shelly Ben-Shushan R, Cohen Z, Beyer AM, Chuyun D, Gutterman DD, Szuchman-Sapir A.) Biochem Biophys Res Commun. 2024 Mar 12;700:149585 PMID: 38290177 SCOPUS ID: 2-s2.0-85183513377 01/30/2024
-
Clinical Implications of COVID-19-Related Endothelial Dysfunction
(Aljadah M, Khan N, Beyer AM, Chen Y, Blanker A, Widlansky ME.) JACC: Advances. August 2024;3(8) SCOPUS ID: 2-s2.0-85197318304 08/01/2024