Ivor J. Benjamin, MD, FAHA, FACC

Publications

• The American Heart Association at 100: A Century of Scientific Progress and the Future of Cardiovascular Science: A Presidential Advisory From the American Heart Association.

  (Elkind MSV, Arnett DK, Benjamin IJ, Eckel RH, Grant AO, Houser SR, Jacobs AK, Jones DW, Robertson RM, Sacco RL, Smith SC Jr, Weisfeldt ML, Wu JC, Jessup M.) Circulation. 2024 Mar 19;149(12):e964-e985 PMID: 38344851 02/12/2024

• Myocardial Strain for the Differentiation of Myocardial Involvement in the Post-Acute Sequelae of COVID-19-A Multiparametric Cardiac MRI Study.

  (Ibrahim EH, Rubenstein J, Sosa A, Stojanovska J, Pan A, North P, Rui H, Benjamin I.) Tomography. 2024 Feb 27;10(3):331-348 PMID: 38535768 PMCID: PMC10974260 SCOPUS ID: 2-s2.0-85188901578 03/27/2024

• Profibrotic COVID-19 subphenotype exhibits enhanced localized ER-dependent HSP47+ expression in cardiac myofibroblasts in situ.

  (Jacobs ER, Ross GR, Padilla N, Pan AY, Liegl M, Puzyrenko A, Lai S, Dai Q, Uche N, Rubenstein JC, North PE, Ibrahim EH, Sun Y, Felix JC, Rui H, Benjamin IJ.) J Mol Cell Cardiol. 2023 Dec;185:1-12 PMID: 37839656 PMCID: PMC11000691 SCOPUS ID: 2-s2.0-85174455933 10/16/2023

• Nuclear damage in LMNA mutant iPSC-derived cardiomyocytes is associated with impaired lamin localization to the nuclear envelope.

  (Wallace M, Zahr H, Perati S, Morsink CD, Johnson LE, Gacita AM, Lai S, Wallrath LL, Benjamin IJ, McNally EM, Kirby TJ, Lammerding J.) Mol Biol Cell. 2023 Aug 16;34(12):mbcE21100527 PMID: 37585285 PMCID: PMC10846625 08/16/2023

• Carvedilol Phenocopies PGC-1α Overexpression to Alleviate Oxidative Stress, Mitochondrial Dysfunction and Prevent Doxorubicin-Induced Toxicity in Human iPSC-Derived Cardiomyocytes.

  (Uche N, Dai Q, Lai S, Kolander K, Thao M, Schibly E, Sendaydiego X, Zielonka J, Benjamin IJ.) Antioxidants (Basel). 2023 Aug 09;12(8) PMID: 37627583 PMCID: PMC10451268 08/26/2023

• Collagen-Specific HSP47+ Myofibroblasts and CD163+ Macrophages Identify Profibrotic Phenotypes in Deceased Hearts With SARS-CoV-2 Infections.

  (Puzyrenko A, Jacobs ER, Padilla N, Devine A, Aljadah M, Gantner BN, Pan AY, Lai S, Dai Q, Rubenstein JC, North PE, Simpson PM, Willoughby RE, O'Meara CC, Flinn MA, Lough JW, Ibrahim EH, Zheng Z, Sun Y, Felix J, Hunt BC, Ross G, Rui H, Benjamin IJ.) J Am Heart Assoc. 2023 Feb 21;12(4):e027990 PMID: 36789856 PMCID: PMC10111490 SCOPUS ID: 2-s2.0-85148479620 02/16/2023

• Penicillin Reactions in Patients With Severe Rheumatic Heart Disease: A Presidential Advisory From the American Heart Association.

  (Sanyahumbi A, Ali S, Benjamin IJ, Karthikeyan G, Okello E, Sable CA, Taubert K, Wyber R, Zuhlke L, Carapetis JR, Beaton AZ, American Heart Association.) J Am Heart Assoc. 2022 Mar;11(5):e024517 PMID: 35049336 PMCID: PMC9075066 01/21/2022

• Impact of the COVID-19 Pandemic on Cardiovascular Science: Anticipating Problems and Potential Solutions: A Presidential Advisory From the American Heart Association.

  (McNally EM, Elkind MSV, Benjamin IJ, Chung MK, Dillon GH, Hernandez AF, Ibeh C, Lloyd-Jones DM, McCullough LD, Wold LE, Wright DR, Wu JC.) Circulation. 2021 Dec 07;144(23):e461-e471 PMID: 34719260 PMCID: PMC10227717 SCOPUS ID: 2-s2.0-85122546616 11/02/2021

• Modulation of muscle redox and protein aggregation rescues lethality caused by mutant lamins.

  (Coombs GS, Rios-Monterrosa JL, Lai S, Dai Q, Goll AC, Ketterer MR, Valdes MF, Uche N, Benjamin IJ, Wallrath LL.) Redox Biol. 2021 Nov 25;48:102196 PMID: 34872044 PMCID: PMC8646998 12/07/2021

• The history and geographic distribution of a KCNQ1 atrial fibrillation risk allele.

  (Hateley S, Lopez-Izquierdo A, Jou CJ, Cho S, Schraiber JG, Song S, Maguire CT, Torres N, Riedel M, Bowles NE, Arrington CB, Kennedy BJ, Etheridge SP, Lai S, Pribble C, Meyers L, Lundahl D, Byrnes J, Granka JM, Kauffman CA, Lemmon G, Boyden S, Scott Watkins W, Karren MA, Knight S, Brent Muhlestein J, Carlquist JF, Anderson JL, Chahine KG, Shah KU, Ball CA, Benjamin IJ, Yandell M, Tristani-Firouzi M.) Nat Commun. 2021 Nov 08;12(1):6442 PMID: 34750360 PMCID: PMC8575962 11/10/2021

• Modulation of muscle redox and protein aggregation rescues lethality caused by mutant lamins

  (Coombs GS, Rios-Monterrosa JL, Lai S, Dai Q, Goll AC, Ketterer MR, Valdes MF, Uche N, Benjamin IJ, Wallrath LL.) Redox Biology. December 2021;48 SCOPUS ID: 2-s2.0-85120438753 12/01/2021

• Hypertriglyceridemia during hospitalization independently associates with mortality in patients with COVID-19.

  (Dai W, Lund H, Chen Y, Zhang J, Osinski K, Jones SZ, Kreuziger LB, López JA, Benjamin IJ, Silverstein RL, Zheng Z.) J Clin Lipidol. 2021;15(5):724-731 PMID: 34470719 PMCID: PMC8353976 SCOPUS ID: 2-s2.0-85114047849 09/03/2021