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Anthony Zamora, PhD

Anthony E. Zamora, PhD

Assistant Professor, Medicine (Hematology and Oncology) and Microbiology & Immunology

Locations

  • MFRC 6072

Contact Information

Education

PhD, Immunology, University of California, Davis, 2015

Research Experience

  • Antigen Presentation
  • CD8-Positive T-Lymphocytes
  • Cell Engineering
  • Disease Models, Animal
  • Flow Cytometry
  • Immunity
  • immunology
  • Immunotherapy
  • Killer Cells, Natural
  • Leukemia, B-Cell
  • Single-Cell Analysis
  • T-Lymphocytes

Research Interests

Research in the Zamora lab spans the fields of viral and cancer immunology, with a special focus on identifying ways to modulate the immune system to more effectively target and eliminate virally infected or cancerous cells. Along these lines, the lab utilizes cellular-based engineering approaches that aim to increase the specificity of immune cells for their targets and at the same time decrease the likelihood of off-target toxicities. A longstanding goal in the lab has also been to help address the current disparities in cancer research by developing reagents, assays, and tools that provide a deeper understanding of the underlying mechanisms that govern antitumor immunity across diverse demographic groups.

Current research in the Zamora lab focuses on: (1) discovering tumor antigens that serve as immunogenic targets, (2) identifying the mechanisms involved in the immune system’s ability to generate antitumor specificities, (3) characterizing the phenotypic, functional, and receptor repertoires of NK cells and neoantigen-specific T cells, and (4) exploring ways to translate these findings in order to expand on the current therapeutic options used to treat cancer.

Publications