Kunal Gupta, MD, PhD, FAANS

Assistant Professor

Locations

Neurosurgery
8701 Watertown Plank Rd.
Milwaukee, WI 53226

Education

Fellowship, Functional and Epilepsy Neurosurgery, Emory University, Atlanta, GA, 2019-2020
Internship & Residency, Neurological Surgery, Oregon Health Sciences University Hospital, Portland, OR, 2012-2019
MBCHB-Doctor of Medicine, University of Cambridge, Cambridge, United Kingdom, 2006

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Biography

Dr. Kunal Gupta specializes in the open and minimally invasive treatment of movement disorders and epilepsy. He graduated with distinction from the University of Cambridge, England. Dr. Gupta trained at Oregon Health & Science University, and completed a fellowship in epilepsy and functional neurosurgery at Emory University, focusing on deep brain stimulation (DBS), stereoelectroencephalography (SEEG), and minimally-invasive laser therapy (LITT) for epilepsy. He actively pursues his research interests, investigating new methods to treat epilepsy and advancing novel surgical techniques. Dr. Gupta’s research work has been published in numerous peer-reviewed journals, including Epilepsia, PNAS, Journal of Neurosurgery, Neuroscience Letters, and Cell Death and Differentiation.

Specialty

Epilepsy and Functional Neurosurgery

Clinical Programs

Research Areas of Interest

Epilepsy
Epilepsy, Temporal Lobe
Neurosciences

Research Interests

Molecular biology of epileptogenesis
Novel indications for deep brain stimulation
Novel surgical techniques in epilepsy surgery

Insights into epileptogenesis from post-traumatic epilepsy.

(Pease M, Gupta K, Moshé SL, Correa DJ, Galanopoulou AS, Okonkwo DO, Gonzalez-Martinez J, Shutter L, Diaz-Arrastia R, Castellano JF.) Nat Rev Neurol. 2024 Apr 03 PMID: 38570704 04/04/2024
Canonical Wnt activator Chir99021 prevents epileptogenesis in the intrahippocampal kainate mouse model of temporal lobe epilepsy

(Mardones MD, Rostam KD, Nickerson MC, Gupta K.) Experimental Neurology. June 2024;376 SCOPUS ID: 2-s2.0-85188911182 06/01/2024
Transcriptome Profiling of the Hippocampal Seizure Network Implicates a Role for Wnt Signaling during Epileptogenesis in a Mouse Model of Temporal Lobe Epilepsy.

(Mardones MD, Gupta K.) Int J Mol Sci. 2022 Oct 10;23(19) PMID: 36233336 PMCID: PMC9569502 SCOPUS ID: 2-s2.0-85139980008 10/15/2022
Globus Pallidus Interna and Ventral Intermediate Nucleus of the Thalamus Deep Brain Stimulation for Adductor Laryngeal Dystonia: a Case Report of Blinded Analyses of Objective Voice Outcomes in 2 Patients.

(Patel RR, Zauber SE, Yadav AP, Witt TC, Halum S, Gupta K.) Neurosurgery. 2022 Apr 01;90(4):457-463 PMID: 35138294 SCOPUS ID: 2-s2.0-85126830952 02/10/2022
Programming Parameters and Techniques in Trigeminal Ganglion Stimulation for Intractable Facial Pain.

(Gupta K, Texakalidis P, Boulis NM.) Neuromodulation. 2021 Aug;24(6):1100-1106 PMID: 33145871 SCOPUS ID: 2-s2.0-85096685914 11/05/2020
Novel Use of Stimulating Fence-Post Technique for Functional Mapping of Subcortical White Matter During Tumor Resection: A Technical Case Series.

(Han SJ, Teton Z, Gupta K, Kawamoto A, Raslan AM.) Oper Neurosurg (Hagerstown). 2020 Sep 01;19(3):264-270 PMID: 32133508 SCOPUS ID: 2-s2.0-85089608106 03/07/2020
Stereotactic MRI-guided laser interstitial thermal therapy for extratemporal lobe epilepsy.

(Gupta K, Cabaniss B, Kheder A, Gedela S, Koch P, Hewitt KC, Alwaki A, Rich C, Ramesha S, Hu R, Drane DL, Gross RE, Willie JT.) Epilepsia. 2020 Aug;61(8):1723-1734 PMID: 32777090 PMCID: PMC8019400 SCOPUS ID: 2-s2.0-85089201160 08/11/2020
Lumbar laminotomy for the intrathecal administration of nusinersen for spinal muscular atrophy: technical note and outcomes.

(Ko D, Blatt D, Karam C, Gupta K, Raslan AM.) J Neurosurg Spine. 2019 Apr 19:1-5 PMID: 31003222 SCOPUS ID: 2-s2.0-85073652817 04/20/2019
Neuronal network remodeling and Wnt pathway dysregulation in the intra-hippocampal kainate mouse model of temporal lobe epilepsy.

(Gupta K, Schnell E.) PLoS One. 2019;14(10):e0215789 PMID: 31596871 PMCID: PMC6785072 SCOPUS ID: 2-s2.0-85073053846 10/10/2019
Delivery Methods for Treatment of Genetic Disorders

(Gupta K, Selden NR.) Nervous System Drug Delivery: Principles and Practice. 25 June 2019:447-461 SCOPUS ID: 2-s2.0-85083811294 06/25/2019
Elucidating Pro-Inflammatory Cytokine Responses after Traumatic Brain Injury in a Human Stem Cell Model.

(Thelin EP, Hall CE, Gupta K, Carpenter KLH, Chandran S, Hutchinson PJ, Patani R, Helmy A.) J Neurotrauma. 2018 Jan 15;35(2):341-352 PMID: 28978285 PMCID: PMC5784793 SCOPUS ID: 2-s2.0-85041057115 10/06/2017
Cortical dysplasia and extratemporal resections in epilepsy

(Gupta K, Selden NR.) Functional Neurosurgery and Neuromodulation. 1 January 2018:129-136 SCOPUS ID: 2-s2.0-85092587662 01/01/2018