Sunila Pradeep, PhD

Publications

• Blocking Oncostatin M receptor abrogates STAT3 mediated integrin signaling and overcomes chemoresistance in ovarian cancer.

  (Geethadevi A, Ku Z, Tsaih SW, Parashar D, Kadamberi IP, Xiong W, Deng H, George J, Kumar S, Mittal S, Zhang N, Pradeep S, An Z, Chaluvally-Raghavan P.) NPJ Precis Oncol. 2024 Jun 05;8(1):127 PMID: 38839865 PMCID: PMC11153533 SCOPUS ID: 2-s2.0-85195471255 06/06/2024

• From Gut to Hormones: Unraveling the Role of Gut Microbiota in (Phyto)Estrogen Modulation in Health and Disease.

  (Kumari N, Kumari R, Dua A, Singh M, Kumar R, Singh P, Duyar-Ayerdi S, Pradeep S, Ojesina AI, Kumar R.) Mol Nutr Food Res. 2024 Mar;68(6):e2300688 PMID: 38342595 SCOPUS ID: 2-s2.0-85184482849 02/12/2024

• Protocol for the isolation of tumor cell-derived extracellular vesicles followed by in vivo metastasis assessment in a murine ovarian cancer model

  (Mittal S, Kumar S, Gupta P, Singh M, Chaluvally-Raghavan P, Pradeep S.) STAR Protocols. 21 June 2024;5(2) SCOPUS ID: 2-s2.0-85187377383 06/21/2024

• Preclinical activity of selinexor in combination with eribulin in uterine leiomyosarcoma.

  (Mittal S, Kadamberi IP, Chang H, Wang F, Kumar S, Tsaih SW, Walker CJ, Chaluvally-Raghavan P, Charlson J, Landesman Y, Pradeep S.) Exp Hematol Oncol. 2023 Sep 15;12(1):78 PMID: 37715291 PMCID: PMC10503035 SCOPUS ID: 2-s2.0-85171339411 09/16/2023

• Overcoming adaptive resistance to anti-VEGF therapy by targeting CD5L.

  (LaFargue CJ, Amero P, Noh K, Mangala LS, Wen Y, Bayraktar E, Umamaheswaran S, Stur E, Dasari SK, Ivan C, Pradeep S, Yoo W, Lu C, Jennings NB, Vathipadiekal V, Hu W, Chelariu-Raicu A, Ku Z, Deng H, Xiong W, Choi HJ, Hu M, Kiyama T, Mao CA, Ali-Fehmi R, Birrer MJ, Liu J, Zhang N, Lopez-Berestein G, de Franciscis V, An Z, Sood AK.) Nat Commun. 2023 Apr 26;14(1):2407 PMID: 37100807 PMCID: PMC10133315 SCOPUS ID: 2-s2.0-85153918496 04/27/2023

• RNA-binding protein FXR1 drives cMYC translation by recruiting eIF4F complex to the translation start site.

  (George J, Li Y, Kadamberi IP, Parashar D, Tsaih SW, Gupta P, Geethadevi A, Chen C, Ghosh C, Sun Y, Mittal S, Ramchandran R, Rui H, Lopez-Berestein G, Rodriguez-Aguayo C, Leone G, Rader JS, Sood AK, Dey M, Pradeep S, Chaluvally-Raghavan P.) Cell Rep. 2023 Mar 28;42(3):112228 PMID: 36884347 PMCID: PMC10233815 SCOPUS ID: 2-s2.0-85149682952 03/09/2023

• Metabolic Reprogramming in Tumor-Associated Macrophages in the Ovarian Tumor Microenvironment.

  (Kumar S, Mittal S, Gupta P, Singh M, Chaluvally-Raghavan P, Pradeep S.) Cancers (Basel). 2022 Oct 25;14(21) PMID: 36358644 PMCID: PMC9656653 SCOPUS ID: 2-s2.0-85141848301 11/12/2022

• Optimized proximity ligation assay (PLA) for detection of RNA-protein complex interactions in cell lines.

  (George J, Mittal S, Kadamberi IP, Pradeep S, Chaluvally-Raghavan P.) STAR Protoc. 2022 Jun 17;3(2):101340 PMID: 35620072 PMCID: PMC9127197 SCOPUS ID: 2-s2.0-85130357879 05/28/2022

• Author Correction: Tuning microtubule dynamics to enhance cancer therapy by modulating FER-mediated CRMP2 phosphorylation.

  (Zheng Y, Sethi R, Mangala LS, Taylor C, Goldsmith J, Wang M, Masuda K, Carrami EM, Mannion D, Miranda F, Herrero-Gonzalez S, Hellner K, Chen F, Alsaadi A, Albukhari A, Fotso DC, Yau C, Jiang D, Pradeep S, Rodriguez-Aguayo C, Lopez-Berestein G, Knapp S, Gray NS, Campo L, Myers KA, Dhar S, Ferguson D, Bast RC Jr, Sood AK, von Delft F, Ahmed AA.) Nat Commun. 2022 Jun 10;13(1):3352 PMID: 35688808 PMCID: PMC9187678 SCOPUS ID: 2-s2.0-85131828825 06/11/2022

• Tumor Derived Extracellular Vesicles Drive T Cell Exhaustion in Tumor Microenvironment through Sphingosine Mediated Signaling and Impacting Immunotherapy Outcomes in Ovarian Cancer.

  (Gupta P, Kadamberi IP, Mittal S, Tsaih SW, George J, Kumar S, Vijayan DK, Geethadevi A, Parashar D, Topchyan P, McAlarnen L, Volkman BF, Cui W, Zhang KYJ, Di Vizio D, Chaluvally-Raghavan P, Pradeep S.) Adv Sci (Weinh). 2022 May;9(14):e2104452 PMID: 35289120 PMCID: PMC9108620 SCOPUS ID: 2-s2.0-85126251446 03/16/2022

• Extracellular vesicle contents as non-invasive biomarkers in ovarian malignancies

  (McAlarnen LA, Gupta P, Singh R, Pradeep S, Chaluvally-Raghavan P.) Molecular Therapy Oncolytics. 15 September 2022;26:347-359 SCOPUS ID: 2-s2.0-85136664501 09/15/2022

• Correction to: Parashar et al. Patient-Derived Ovarian Cancer Spheroids Rely on PI3K-AKT Signaling Addiction for Cancer Stemness and Chemoresistance (Cancers, (2022), 14, 958)

  (Parashar D, Geethadevi A, Mittal S, McAlarnen LA, George J, Kadamberi IP, Gupta P, Uyar DS, Hopp EE, Drendel H, Bishop EA, Bradley WH, Bone KM, Rader JS, Pradeep S, Chaluvally-Raghavan P.) Cancers. May-2 2022;14(10) SCOPUS ID: 2-s2.0-85129951244 05/01/2022