Peter S. LaViolette, PhD, MS
Professor; Director, Quantitative Imaging Laboratory, Medical College of Wisconsin; Section of Imaging Research, Division of Imaging Sciences
Locations
- Medical College of Wisconsin
Department of Radiology
Contact Information
Education
PhD, Biophysics, Medical College of Wisconsin, Milwaukee, WI, 2011
MA, MS, Physics, University of Massachusetts, Amherst, MA, 2005
BS, Physics, St. Norbert College, De Pere, WI, 2003
Research Interests
The overall goal of my lab’s research is creating and validating imaging techniques that improve both patient outcome and treatment efficacy. I primarily work with neurological diseases such as brain cancer and epilepsy in a translational setting, collaborating with clinicians for the betterment of patient care.
Our brain cancer research has been focused on characterizing brain tumor cellularity and vascularity through imaging methods such as diffusion and perfusion MRI. The neuro-imaging techniques we develop are used to determine whether brain tumors respond to therapy or signal when brain tumors are progressing. In addition to patient outcome studies, we study the histological features responsible for the imaging characteristics measures in-vivo. This provides us with a validation technique for assessing our imaging biomarkers.
My epilepsy research is mainly focused on development of image processing techniques meant to help clinicians better plan surgery and map out brain function.
Publications
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Radio-pathomic estimates of cellular growth kinetics predict survival in recurrent glioblastoma.
(Oshima S, Yao J, Bobholz S, Nagaraj R, Raymond C, Teraishi A, Guenther AM, Kim A, Sanvito F, Cho NS, C Eldred BS, Connelly JM, Nghiemphu PL, Lai A, Salamon N, Cloughesy TF, LaViolette PS, Ellingson BM.) CNS Oncol. 2024 Dec 31;13(1):2415285 PMID: 39535237 PMCID: PMC11562955 SCOPUS ID: 2-s2.0-85209813692 11/13/2024
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(Bobholz SA, Lowman AK, Connelly JM, Duenweg SR, Winiarz A, Nath B, Kyereme F, Brehler M, Bukowy J, Coss D, Lupo JM, Phillips JJ, Ellingson BM, Krucoff MO, Mueller WM, Banerjee A, LaViolette PS.) Neurosurgery. 2024 Sep 01;95(3):537-547 PMID: 38501824 PMCID: PMC11302944 SCOPUS ID: 2-s2.0-85201436914 03/19/2024
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(Shalom ES, Kim H, van der Heijden RA, Ahmed Z, Patel R, Hormuth DA 2nd, DiCarlo JC, Yankeelov TE, Sisco NJ, Dortch RD, Stokes AM, Inglese M, Grech-Sollars M, Toschi N, Sahoo P, Singh A, Verma SK, Rathore DK, Kazerouni AS, Partridge SC, LoCastro E, Paudyal R, Wolansky IA, Shukla-Dave A, Schouten P, Gurney-Champion OJ, Jiřík R, Macíček O, Bartoš M, Vitouš J, Das AB, Kim SG, Bokacheva L, Mikheev A, Rusinek H, Berks M, Hubbard Cristinacce PL, Little RA, Cheung S, O'Connor JPB, Parker GJM, Moloney B, LaViolette PS, Bobholz S, Duenweg S, Virostko J, Laue HO, Sung K, Nabavizadeh A, Saligheh Rad H, Hu LS, Sourbron S, Bell LC, Fathi Kazerooni A.) Magn Reson Med. 2024 May;91(5):1803-1821 PMID: 38115695 12/20/2023
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(Bobholz SA, Hoefs A, Hamburger J, Lowman AK, Winiarz A, Duenweg SR, Kyereme F, Connelly J, Coss D, Krucoff M, Banerjee A, LaViolette PS.) J Neurooncol. 2024 Apr;167(2):243 PMID: 38498261 PMCID: PMC11023959 SCOPUS ID: 2-s2.0-85187929260 03/19/2024
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Morphologic features of prostate cancer-encased native vessels: An image analysis study.
(Fernandez Gonzalez De La Vega C, Duenweg S, Jain P, Rubenstein SI, Bobholz S, Barrett MJ, LaViolette PS, Iczkowski KA.) Pathol Res Pract. 2024 Apr;256:155239 PMID: 38461692 03/11/2024
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(Bobholz SA, Hoefs A, Hamburger J, Lowman AK, Winiarz A, Duenweg SR, Kyereme F, Connelly J, Coss D, Krucoff M, Banerjee A, LaViolette PS.) J Neurooncol. 2024 Apr;167(2):233-241 PMID: 38372901 PMCID: PMC11024025 SCOPUS ID: 2-s2.0-85185314152 02/19/2024
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The Epigenetic Evolution of Glioma Is Determined by the IDH1 Mutation Status and Treatment Regimen.
(Malta TM, Sabedot TS, Morosini NS, Datta I, Garofano L, Vallentgoed W, Varn FS, Aldape K, D'Angelo F, Bakas S, Barnholtz-Sloan JS, Gan HK, Hasanain M, Hau AC, Johnson KC, Cazacu S, deCarvalho AC, Khasraw M, Kocakavuk E, Kouwenhoven MCM, Migliozzi S, Niclou SP, Niers JM, Ormond DR, Paek SH, Reifenberger G, Sillevis Smitt PA, Smits M, Stead LF, van den Bent MJ, Van Meir EG, Walenkamp A, Weiss T, Weller M, Westerman BA, Ylstra B, Wesseling P, Lasorella A, French PJ, Poisson LM, Consortium The GLASS, Verhaak RGW, Iavarone A, Noushmehr H.) Cancer Res. 2024 Mar 04;84(5):741-756 PMID: 38117484 PMCID: PMC10911804 12/20/2023
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(Duenweg SR, Brehler M, Lowman AK, Bobholz SA, Kyereme F, Winiarz A, Nath B, Iczkowski KA, Jacobsohn KM, LaViolette PS.) Lab Invest. 2023 Dec;103(12):100269 PMID: 37898290 PMCID: PMC10872376 10/29/2023
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(LoCastro E, Paudyal R, Konar AS, LaViolette PS, Akin O, Hatzoglou V, Goh AC, Bochner BH, Rosenberg J, Wong RJ, Lee NY, Schwartz LH, Shukla-Dave A.) Tomography. 2023 Nov 03;9(6):2052-2066 PMID: 37987347 PMCID: PMC10661267 11/21/2023
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(Duenweg SR, Bobholz SA, Barrett MJ, Lowman AK, Winiarz A, Nath B, Stebbins M, Bukowy J, Iczkowski KA, Jacobsohn KM, Vincent-Sheldon S, LaViolette PS.) Cancers (Basel). 2023 Sep 06;15(18) PMID: 37760407 PMCID: PMC10526331 09/28/2023
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(Duenweg SR, Bobholz SA, Lowman AK, Stebbins MA, Winiarz A, Nath B, Kyereme F, Iczkowski KA, LaViolette PS.) J Pathol Inform. 2023;14:100321 PMID: 37496560 PMCID: PMC10365953 07/27/2023