Y. David Seo, MD

Publications

• Randomized Placebo-Controlled, Biomarker-Stratified Phase Ib Microbiome Modulation in Melanoma: Impact of Antibiotic Preconditioning on Microbiome and Immunity.

  (Glitza IC, Seo YD, Spencer CN, Wortman JR, Burton EM, Alayli FA, Loo CP, Gautam S, Damania A, Densmore J, Fairchild J, Cabanski CR, Wong MC, Peterson CB, Weiner B, Hicks N, Aunins J, McChalicher C, Walsh E, Tetzlaff MT, Hamid O, Ott PA, Boland GM, Sullivan RJ, Grossmann KF, Ajami NJ, LaVallee T, Henn MR, Tawbi HA, Wargo JA.) Cancer Discov. 2024 Jul 01;14(7):1161-1175 PMID: 38588588 PMCID: PMC11215408 SCOPUS ID: 2-s2.0-85197893321 04/08/2024

• Local Immunoradiotherapy in Patients With Metastatic Soft-Tissue Sarcoma-Reply.

  (Seo YD, Pollack SM.) JAMA Oncol. 2024 Jun 01;10(6):830-831 PMID: 38602667 SCOPUS ID: 2-s2.0-85190480277 04/11/2024

• Intratumoral T-cell receptor repertoire composition predicts overall survival in patients with pancreatic ductal adenocarcinoma.

  (Pothuri VS, Hogg GD, Conant L, Borcherding N, James CA, Mudd J, Williams G, Seo YD, Hawkins WG, Pillarisetty VG, DeNardo DG, Fields RC.) Oncoimmunology. 2024;13(1):2320411 PMID: 38504847 PMCID: PMC10950267 SCOPUS ID: 2-s2.0-85188105419 03/20/2024

• Modulating a prebiotic food source influences inflammation and immune-regulating gut microbes and metabolites: insights from the BE GONE trial.

  (Zhang X, Irajizad E, Hoffman KL, Fahrmann JF, Li F, Seo YD, Browman GJ, Dennison JB, Vykoukal J, Luna PN, Siu W, Wu R, Murage E, Ajami NJ, McQuade JL, Wargo JA, Long JP, Do KA, Lampe JW, Basen-Engquist KM, Okhuysen PC, Kopetz S, Hanash SM, Petrosino JF, Scheet P, Daniel CR.) EBioMedicine. 2023 Dec;98:104873 PMID: 38040541 PMCID: PMC10755114 SCOPUS ID: 2-s2.0-85179481195 12/02/2023

• Toll-Like Receptor 4 Agonist Injection With Concurrent Radiotherapy in Patients With Metastatic Soft Tissue Sarcoma: A Phase 1 Nonrandomized Controlled Trial.

  (Seo YD, Lu H, Black G, Smythe K, Yu Y, Hsu C, Ng J, Hermida de Viveiros P, Warren EH, Schroeder BA, O'Malley RB, Cranmer LD, Loggers ET, Wagner MJ, Bonham L, Pillarisetty VG, Kane G, Berglund P, Hsu FJ, Mi X, Alexiev BA, Pierce RH, Riddell SR, Jones RL, Ter Meulen J, Kim EY, Pollack SM.) JAMA Oncol. 2023 Dec 01;9(12):1660-1668 PMID: 37824131 PMCID: PMC10570919 SCOPUS ID: 2-s2.0-85179665501 10/12/2023

• Efficacy of immune checkpoint inhibitors for the treatment of advanced melanoma in patients with concomitant chronic lymphocytic leukemia.

  (Cass SH, Tobin JWD, Seo YD, Gener-Ricos G, Keung EZ, Burton EM, Davies MA, McQuade JL, Lazar AJ, Mason R, Millward M, Sandhu S, Khoo C, Warburton L, Guerra V, Haydon A, Dearden H, Menzies AM, Carlino MS, Smith JL, Mollee P, Burgess M, Mapp S, Keane C, Atkinson V, Parikh SA, Markovic SN, Ding W, Call TG, Hampel PJ, Long GV, Wargo JA, Ferrajoli A.) Ann Oncol. 2023 Sep;34(9):796-805 PMID: 37414216 PMCID: PMC11289780 SCOPUS ID: 2-s2.0-85167984912 07/07/2023

• Using gut microorganisms to treat cancer.

  (Seo YD, Ajami N, Wargo JA.) Nat Med. 2023 Aug;29(8):1910-1911 PMID: 37420098 SCOPUS ID: 2-s2.0-85164488430 07/08/2023

• From bugs to drugs: Bacterial 3-IAA enhances efficacy of chemotherapy in pancreatic cancer.

  (Seo YD, Wargo JA.) Cell Rep Med. 2023 May 16;4(5):101039 PMID: 37196631 PMCID: PMC10213830 SCOPUS ID: 2-s2.0-85159151289 05/18/2023

• Blockade of interleukin 10 potentiates antitumour immune function in human colorectal cancer liver metastases.

  (Sullivan KM, Jiang X, Guha P, Lausted C, Carter JA, Hsu C, Labadie KP, Kohli K, Kenerson HL, Daniel SK, Yan X, Meng C, Abbasi A, Chan M, Seo YD, Park JO, Crispe IN, Yeung RS, Kim TS, Gujral TS, Tian Q, Katz SC, Pillarisetty VG.) Gut. 2023 Feb;72(2):325-337 PMID: 35705369 PMCID: PMC9872249 SCOPUS ID: 2-s2.0-85132593579 06/16/2022

• Monitoring and Modulating Diet and Gut Microbes to Enhance Response and Reduce Toxicity to Cancer Treatment.

  (Knisely A, Seo YD, Wargo JA, Chelvanambi M.) Cancers (Basel). 2023 Jan 27;15(3) PMID: 36765735 PMCID: PMC9913233 02/12/2023

• Quality of superior mesenteric and hepatic artery dissection in robotic pancreatoduodenectomy for pancreatic cancer.

  (Ikoma N, Seo YD, Newhook TE, Maxwell JE, Kim MP, Tran Cao HS, Tzeng CD, Chun YS, Lee JE, Vauthey JN, Katz MHG.) J Hepatobiliary Pancreat Sci. 2023 Jan;30(1):e1-e2 PMID: 35950790 SCOPUS ID: 2-s2.0-85135822625 08/12/2022

• Preoperative therapy for pancreatic adenocarcinoma-precision beyond anatomy.

  (Seo YD, Katz MHG.) Cancer. 2022 Aug 15;128(16):3041-3056 PMID: 35679197 SCOPUS ID: 2-s2.0-85131541270 06/10/2022