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Medical College of Wisconsin School of Graduate Studies

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Medical College of Wisconsin School of Graduate Studies

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Archi Paul

Archi Paul

Graduate Student

Program

Biochemistry

Contact Information

arpaul@mcw.edu

Biography

Mentor: Elizabeth Sweeny, PhD
Year Entered MCW: 2023
Previous Education: University of Dhaka

Research Interests

My research investigates the role of NADPH oxidase 5 (NOX-5) in diseases. NOX5 is a heme-containing enzyme activated by calcium that plays a crucial role in numerous physiological functions. NOX-5 is associated with various diseases, such as cancer and cardiovascular disorders. In the lab, we focus on NOX-5's interactions with mitochondrial and cytoskeletal proteins, which are crucial for understanding its role in health and pathology. The goal is to uncover new therapeutic targets and biomarkers for NOX-5 induced diseases.

Publications

MM Rahman, S Biswas, KJ Islam, Archi Sundar Paul, SK Mahato, MA Ali, MA Halim, “Antiviral phytochemicals as potent inhibitors against NS3 protease of dengue virus”, Computers in Biology and Medicine 2021 ;134 (May), 104492. PMID: 34022487
Archi Sundar Paul, R Islam, MR Parves, AA Mamun, I Shahriar, MI Hossain, MN Hossain, MA Ali, MA Halim, “Cysteine focused covalent inhibitors against the main protease of SARS-CoV-2”, Journal of Biomolecular Structure and Dynamics 2020; 40(4):1639-1658. PMID: 33047658
R Islam, MR Parves, Archi Sundar Paul, N Uddin, MS Rahman, AA Mamun, MN Hossain, MA Ali, MA Halim, “A molecular modeling approach to identify effective antiviral phytochemicals against the main protease of SARS-CoV-2”, Journal of Biomolecular Structure and Dynamics 2020; 39(9):3213-3224. PMID: 32340562