Christopher Monti

Mass spectrometry-proteomics, virology

Research Experience

Medical College of Wisconsin, 2020-2024
Advisor: Scott Terhune, PhD, and Ranjan Dash, PhD
Project: Computational Modeling of Physiologic and Pathophysiologic States. Bottom-up and top-down computational modeling approaches to study CMV retinitis (F30AI179084)

NIH-NEI, 2017-2018
Advisors: Anand Swaroop, PhD and Samantha Papal, PhD
Project: Retinal degeneration

Duke University, Department of Evolutionary Anthropology, 2015-2017
Advisor: Angel Zeininger, PhD
Project: Ontogeny of Locomotion 

Publications

Monti CE, Hong SK, Audi SH, Lee W, Joshi A, Terhune SS, Kim J, Dash RK. Assessing the degree of hepatic ischemia-reperfusion injury using PBPK modeling of sodium fluorescein disposition in ex vivo machine-perfused livers. Am J Physiol Gastrointest Liver Physiol. 2024 Jun 25. doi: 10.1152/ajpgi.00048.2024. Epub ahead of print. PMID: 38917324.

Mokry RL, Monti CE, Rosas-Rogers S, Schumacher ML, Dash RK, Terhune SS. Replication efficiencies of human cytomegalovirus-infected epithelial cells are dependent on source of virus production. bioRxiv [Preprint]. 2024 Mar 19:2024.03.19.585739. doi: 10.1101/2024.03.19.585739. PMID: 38562837; PMCID: PMC10983881.

Monti C, Audi SH, Womack J, Hong SK, Yang Y, Kim J, Dash RK. Physiologically-Based Pharmacokinetic Modeling of Blood Clearance of Liver Fluorescent Markers for the Assessment of the Degree of Hepatic Ischemia-Reperfusion Injury. Annu Int Conf IEEE Eng Med Biol Soc. 2023 Jul;2023:1-6. doi: 10.1109/EMBC40787.2023.10340273. PMID: 38082711.

Monti CE, Mokry RL, Schumacher ML, Dash RK, Terhune SS. Computational modeling of protracted HCMV replication using genome substrates and protein temporal profiles. Proc Natl Acad Sci U S A. 2022 Aug 30;119(35):e2201787119. doi: 10.1073/pnas.2201787119. Epub 2022 Aug 22. PMID: 35994667; PMCID: PMC9437303.

Papal S, Monti CE, Tennison ME, Swaroop A. Molecular dissection of cone photoreceptor-enriched genes encoding transmembrane and secretory proteins. J Neurosci Res. 2019 Jan;97(1):16-28. doi: 10.1002/jnr.24329. Epub 2018 Sep 27. PMID: 30260491; PMCID: PMC6239890.

Meeting Abstracts

Monti CE, Audi SH, Womack J, Hong SK, Yang Y, Kim J, Dash RK. Physiologically-Based Pharmacokinetic Modeling of Blood Clearance of Liver Fluorescent Markers for the Assessment of the Degree of Hepatic Ischemia-Reperfusion Injury. IEEE-EMBC. Sydney. 2023. [Oral]

General Interests

Star Wars, fencing, snowboarding, music, aviation