Gopika SenthilKumar

Cardiovascular physiology, health education, surgical outcomes and quality improvement

Research Experience

Medical College of Wisconsin, 2021-2024
PhD Advisors: Julie Freed, MD, PhD and David Gutterman, MD
Project: The necessary role of ceramide formation and its regulation by estrogen in the human microcirculation (AHA)

University of Wisconsin, Madison, 2017-2019
Advisors: Randall Kimple MD PhD
Projects: Inhibition of fibroblast growth factor receptor using AZD4547 radiosensitizes Head and Neck Cancer and Lung Cancer. Autophagy's role in Head and Neck Cancer’s therapeutic resistance to radiation and cetuximab

University of Wisconsin, Madison, 2015-2016
Advisors: Gillian McLellan BVMS PhD
Project: 3D reconstruction of retinal histology images to track patterns of ganglion cell loss 

Publications

SenthilKumar G, Verhagen NB, Wang TS, Dream SY, Kothari AN. Bridging the Gap: Trainee Reflections About Navigating Otherness in Academic Surgery. J Surg Res. 2023 Nov;291:A1-A3. doi: 10.1016/j.jss.2023.04.006. Epub 2023 May 20. PMID: 37217382.

SenthilKumar G, Mathieu NM, Freed JK, Sigmund CD, Gutterman DD. Addressing the decline in graduate students' mental well-being. Am J Physiol Heart Circ Physiol. 2023 Oct 1;325(4):H882-H887. doi: 10.1152/ajpheart.00466.2023. Epub 2023 Aug 25. PMID: 37624099.

SenthilKumar G, Sommers KC, He Y, Stark K, Craig T, Keval A, Shah N, Patel K, Meurer J. Student Leadership Development Initiative for Medical Students: Lessons Learned From Transitioning to Virtual Modalities. J Med Educ Curric Dev. 2023 Sep 7;10:23821205231200731. doi: 10.1177/23821205231200731. PMID: 37692559; PMCID: PMC10486220.

SenthilKumar G, Merrill J, Maduekwe UN, Cloyd JM, Fournier K, Abbott DE, Zafar N, Patel S, Johnston F, Dineen S, Baumgartner J, Grotz TE, Maithel SK, Raoof M, Lambert L, Hendrix R, Kothari AN. Prediction of Early Recurrence Following CRS/HIPEC in Patients With Disseminated Appendiceal Cancer. J Surg Res. 2023 Sep 2;292:275-288. doi: 10.1016/j.jss.2023.06.054. Epub ahead of print. PMID: 37666090.

SenthilKumar G, Kothari AN, Maduekwe UN, Fournier K, Abbott DE, Wilson GC, Patel SH, Greer J, Johnston F, Dineen SP, Powers BD, Baumgartner J, Veerapong J, Leiting J, Grotz TE, Maithel SK, Staley C, Raoof M, Lambert L, Lee A, Kim A, Cloyd JM, Mogal H. ASO Visual Abstract: Validation of the AJCC 8th Edition Staging System for Disseminated Appendiceal Cancer Patients Treated with Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy-A Multi-institutional Analysis. Ann Surg Oncol. 2023 Sep;30(9):5756-5757. doi: 10.1245/s10434-023-13829-1. PMID: 37423927.

SenthilKumar G, Cloyd JM, Mogal H. ASO Author Reflections: AJCC 8th Edition Performs Well in Predicting Outcomes Among Patients with Disseminated Appendiceal Cancer Undergoing CRS/HIPEC. Ann Surg Oncol. 2023 Sep;30(9):5754-5755. doi: 10.1245/s10434-023-13740-9. Epub 2023 Jun 15. PMID: 37322281.

SenthilKumar G, Kothari AN, Maduekwe UN, Fournier K, Abbott DE, Wilson GC, Patel SH, Greer J, Johnston F, Dineen SP, Powers BD, Baumgartner J, Veerapong J, Leiting J, Grotz TE, Maithel SK, Staley C, Raoof M, Lambert L, Lee A, Kim A, Cloyd JM, Mogal H. Validation of the AJCC 8th Edition Staging System for Disseminated Appendiceal Cancer Patients Treated with Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy: A Multi-institutional Analysis. Ann Surg Oncol. 2023 Sep;30(9):5743-5753. doi: 10.1245/s10434-023-13697-9. Epub 2023 Jun 9. PMID: 37294386.

SenthilKumar G, Heisner JS, Schlaak R, Mishra J, Katunaric B, Pedersen LN, Lavine K, Javaheri A, Camara AKS, Bergom C. Targeted Cardiac Ionizing Radiation in Dahl Salt-Sensitive Rats Can Improve Recovery From Ischemic Injury. JACC Basic Transl Sci. 2023 Aug 28;8(8):1025-1027. doi: 10.1016/j.jacbts.2023.07.004. PMID: 37719423; PMCID: PMC10504396.

Verhagen NB, SenthilKumar G, Jaraczewski T, Koerber NK, Merrill JR, Flitcroft MA, Szabo A, Banerjee A, Yang X, Taylor BW, Figueroa Castro CE, Yen TWF, Clarke CN, Lauer K, Pfeifer KJ, Gould JC, Kothari AN; N3C Consortium. Severity of Prior COVID-19 is Associated with Postoperative Outcomes Following Major Inpatient Surgery. Ann Surg. 2023 Jul 21. doi: 10.1097/SLA.0000000000006035. Epub ahead of print. PMID: 37476995.

SenthilKumar G, Madhusudhana S, Flitcroft M, Sheriff S, Thalji S, Merrill J, Clarke CN, Maduekwe UN, Tsai S, Christians KK, Gamblin TC, Kothari AN. Automated machine learning (AutoML) can predict 90-day mortality after gastrectomy for cancer. Sci Rep. 2023 Jul 8;13(1):11051. doi: 10.1038/s41598-023-37396-3. PMID: 37422500; PMCID: PMC10329647.

SenthilKumar G, Katunaric B, Zirgibel Z, Lindemer B, Jaramillo-Torres MJ, Bordas-Murphy H, Schulz ME, Pearson PJ, Freed JK. Necessary Role of Acute Ceramide Formation in The Human Microvascular Endothelium During Health and Disease. bioRxiv [Preprint]. 2023 Jun 6:2023.06.02.543341. doi: 10.1101/2023.06.02.543341. PMID: 37333082; PMCID: PMC10274701.

SenthilKumar G*, Verhagen NB*, Sheriff SA, Yang X, Figueroa Castro CE, Szabo A, Taylor BW, Wainaina N, Lauer K, Gould JC, Kothari AN; N3C Consortium. Preoperative SARS-CoV-2 infection increases risk of early postoperative cardiovascular complications following noncardiac surgery. Am J Physiol Heart Circ Physiol. 2023 Jun 1;324(6):H721-H731. doi: 10.1152/ajpheart.00097.2023. Epub 2023 Mar 17. PMID: 36930659; PMCID: PMC10151044.

SenthilKumar G, Zirgibel Z, Cohen KE, Katunaric B, Jobe AM, Shult CG, Limpert RH, Freed JK. Ying and Yang of Ceramide in the Vascular Endothelium. Arterioscler Thromb Vasc Biol. 2024 Jun 20;. doi: 10.1161/ATVBAHA.124.321158. [Epub ahead of print] Review. PubMed PMID: 38899471

Benck KN*, SenthilKumar G*, Steely AM, Pereira SJ, DiChiacchio L. Professional Development for Women in Cardiothoracic Surgery. Ann Thorac Surg. 2024 Jun 14;. doi: 10.1016/j.athoracsur.2024.05.039. [Epub ahead of print] PubMed PMID: 38880270. *Co-First Authors

SenthilKumar G, Hammond ST, Zirgibel Z, Cohen KE, Beyer AM, Freed JK. Is the peripheral microcirculation a window into the human coronary microvasculature? J Mol Cell Cardiol. 2024 Aug;193:67-77. doi: 10.1016/j.yjmcc.2024.06.002. Epub 2024 Jun 5. PMID: 38848808; PMCID: PMC11260236.

SenthilKumar G, Zirgibel Z, Cohen KE, Katunaric B, Jobe AM, Shult CG, Limpert RH, Freed JK. Ying and Yang of Ceramide in the Vascular Endothelium. Arterioscler Thromb Vasc Biol. 2024 Aug;44(8):1725-1736. doi: 10.1161/ATVBAHA.124.321158. Epub 2024 Jun 20. PMID: 38899471; PMCID: PMC11269027.

SenthilKumar G, Limpert RH, Lindemer BJ, Freed JK. Acetylcholine-Induced Dilation in Human Arterioles Requires Ceramide Formation. Arterioscler Thromb Vasc Biol. 2024 Aug;44(8):1895-1897. doi: 10.1161/ATVBAHA.124.320916. Epub 2024 Jun 27. PMID: 38934116; PMCID: PMC11268997.

Katunaric B, SenthilKumar G, Stehula FJ, Werthman A, Bordas-Murphy H, Freed JK. Noninvasive assessment of human microvascular function in health and disease using incident dark-field microscopy. Am J Physiol Heart Circ Physiol. 2024 Jul 1;327(1):H261-H267. doi: 10.1152/ajpheart.00292.2024. Epub 2024 May 24. PMID: 38787388.

SenthilKumar G. Empowering Health Professions Trainees to Address Difficult Topics. Acad Med. 2024 Jun 1;99(6):e32. doi: 10.1097/ACM.0000000000005572. Epub 2023 Nov 14. PubMed PMID: 37967274.

SenthilKumar G, Verhagen NB, Nimmer K, Yang X, Figueroa Castro CE, Szabo A, Taylor BW, Wainaina N, Gould JC, Kothari AN. Risk of Early Postoperative Cardiovascular and Cerebrovascular Complication in Patients with Preoperative COVID-19 Undergoing Cancer Surgery. J Am Coll Surg. 2024 Jun 1;238(6):1085-1097. doi: 10.1097/XCS.0000000000001039. Epub 2024 Feb 13. PubMed PMID: 38348959.

SenthilKumar G, Schottstaedt AM, Peterson LL, Pedersen LN, Chitambar CR, Vistocky A, Banerjee A, Longo JM, Kelly T, Currey A, Stolley MR, Bergom C. Stay on Track: A Pilot Randomized Control Trial on the Feasibility of a Diet and Exercise Intervention in Patients with Breast Cancer Receiving Radiotherapy. Cancer Res Commun. 2024 May 7;4(5):1211-1226. doi: 10.1158/2767-9764.CRC-23-0148. PubMed PMID: 38530195; PubMed Central PMCID: PMC11075661.

SenthilKumar G, Katunaric B, Zirgibel Z, Lindemer B, Jaramillo-Torres MJ, Bordas-Murphy H, Schulz ME, Pearson PJ, Freed JK. Necessary Role of Ceramides in the Human Microvascular Endothelium During Health and Disease. Circ Res. 2024 Jan 5;134(1):81-96. doi: 10.1161/CIRCRESAHA.123.323445. Epub 2023 Dec 1. PubMed PMID: 38037825; PubMed Central PMCID: PMC10766100.

Jaraczewski TJ, SenthilKumar G, Ramamurthi A, Nimmer K, Yang X, Kothari AN. Teaming with artificial intelligence to support global cancer surgical care. J Surg Oncol. 2023 Nov;128(6):943-946. doi: 10.1002/jso.27442. PubMed PMID: 37818910.

SenthilKumar G, Katunaric B, Bordas-Murphy H, Sarvaideo J, Freed JK. Estrogen and the Vascular Endothelium: The Unanswered Questions. Endocrinology. 2023 Apr 17;164(6):bqad079. doi: 10.1210/endocr/bqad079. PMID: 37207450; PMCID: PMC10230790.

Verhagen NB, SenthilKumar G, Jaraczewski T, Koerber NK, Merrill JR, Flitcroft MA, Szabo A, Banerjee A, Yang X, Taylor BW, Castro CEF, Yen TWF, Clarke CN, Lauer K, Pfeifer KJ, Gould JC, Kothari AN. Severity of Prior COVID-19 Infection is Associated with Postoperative Outcomes Following Major Inpatient Surgery. medRxiv [Preprint]. 2023 Apr 17:2023.04.12.23288412. doi: 10.1101/2023.04.12.23288412. Update in: Ann Surg. 2023 Jul 21; PMID: 37131614; PMCID: PMC10153306.

SenthilKumar G, Katunaric B, Bordas-Murphy H, Young M, Doren EL, Schulz ME, Widlansky ME, Freed JK. 17β-Estradiol promotes sex-specific dysfunction in isolated human arterioles. Am J Physiol Heart Circ Physiol. 2023 Mar 1;324(3):H330-H337. doi: 10.1152/ajpheart.00708.2022. Epub 2023 Jan 6. PMID: 36607795; PMCID: PMC9925162.

SenthilKumar G, Peraci MMS. Leveraging Virtual Platforms to Overcome the Minority Tax Among International Medical Students and Professionals. WMJ. 2022 Dec;121(4):251. PMID: 36637832.

SenthilKumar G*, Gutierrez-Huerta CA*, Freed JK, Beyer AM, Fancher IS, LeBlanc AJ. New developments in translational microcirculatory research. Am J Physiol Heart Circ Physiol. 2022 Dec 1;323(6):H1167-H1175. doi: 10.1152/ajpheart.00566.2022. Epub 2022 Oct 28. PMID: 36306213; PMCID: PMC9678417.

Katunaric B, SenthilKumar G, Schulz ME, De Oliveira N, Freed JK. S1P (Sphingosine-1-Phosphate)-Induced Vasodilation in Human Resistance Arterioles During Health and Disease. Hypertension. 2022 Oct;79(10):2250-2261. doi: 10.1161/HYPERTENSIONAHA.122.19862. Epub 2022 Aug 22. PMID: 36070401; PMCID: PMC9473289.

Buss R*, SenthilKumar G*, Bouchard M, Bowder A, Marquart J, Cooke-Barber J, Vore E, Beals D, Raval M, Rich BS, Goldstein S, Van Arendonk K. Geographic barriers to children's surgical care: A systematic review of existing evidence. J Pediatr Surg. 2022 Sep;57(9):107-117. doi: 10.1016/j.jpedsurg.2021.11.024. Epub 2021 Dec 3. PMID: 34963510.

SenthilKumar G, Rokkas CK, Sheinin YM, Linsky PL. Rare and complicated functional posterior mediastinal paraganglioma. BMJ Case Rep. 2022 Jun 7;15(6):e250500. doi: 10.1136/bcr-2022-250500. PMID: 35672059; PMCID: PMC9174829.

Jaber Chehayeb R, SenthilKumar G, Saade Z, Gallo Marin B, Aghagoli G, Virji AZ. Examining the First Peer-to-Peer Mentorship Program (F1Doctors) for International Medical Students. J Interdiscip Stud Educ. 2022 Apr 16;11(1):102-125. PMID: 36405890; PMCID: PMC9673072.

Cohen KE, Katunaric B, Schulz ME, SenthilKumar G, Young MS, Mace JE, Freed JK. Role of Adiponectin Receptor 1 in Promoting Nitric Oxide-Mediated Flow-Induced Dilation in the Human Microvasculature. Front Pharmacol. 2022 Apr 4;13:875900. doi: 10.3389/fphar.2022.875900. PMID: 35444544; PMCID: PMC9014203.

Cohen KE, Katunaric B, SenthilKumar G, McIntosh JJ, Freed JK. Vascular endothelial adiponectin signaling across the life span. Am J Physiol Heart Circ Physiol. 2022 Jan 1;322(1):H57-H65. doi: 10.1152/ajpheart.00533.2021. Epub 2021 Nov 19. PMID: 34797171; PMCID: PMC8698498.

Nonarath HJ* and Hall AE*, SenthilKumar G, Abroe B, Eells JT, Liedhegner ES. 670nm photobiomodulation modulates bioenergetics and oxidative stress, in rat Müller cells challenged with high glucose. PLoS One. 2021 Dec 3;16(12):e0260968. doi: 10.1371/journal.pone.0260968. PMID: 34860856; PMCID: PMC8641888.

Schlaak RA, Frei A, SenthilKumar G, Tsaih SW, Wells C, Mishra J, Flister MJ, Camara AKS, Bergom C. Differences in Expression of Mitochondrial Complexes Due to Genetic Variants May Alter Sensitivity to Radiation-Induced Cardiac Dysfunction. Front Cardiovasc Med. 2020 Mar 5;7:23. doi: 10.3389/fcvm.2020.00023. PMID: 32195269; PMCID: PMC7066205.

Schlaak RA, SenthilKumar G, Boerma M, Bergom C. Advances in Preclinical Research Models of Radiation-Induced Cardiac Toxicity. Cancers (Basel). 2020 Feb 11;12(2):415. doi: 10.3390/cancers12020415. PMID: 32053873; PMCID: PMC7072196.

*co-first authors

Meeting Abstracts

Freed JK, SenthilKumar G, Durand M. Promoting Resiliency to Stress in the Human Microcirculation. 15th Mechanisms Of VasoDilation/Endothelium-Dependent Hyperpolarization meeting (MOVD/EDH 2024). Oxford, UK. July 2024. [Keynote Oral]

SenthilKumar G, Machado K, Capotosto S, . . . Peraci M. A National Student-Led Platform for International Pre-Health Students: Mentee Feedback from a Year in Review. 26th Annual Meeting of the International Association of Medical Science Educators. June 2022. Denver Colorado. [Poster]

SenthilKumar G, Verhagen N, Wolfrath N, . . . Anai Kothari. Importance Of Addressing Racial Heterogeneity Prior To Deploying Machine Learning Models For Postoperative Risk Prediction In Gastric Cancer. Scientific Forum at American College of Surgeons Clinical Congress 2024. San Francisco. October 2024. [Oral]

SenthilKumar G, Xing Y, Nataliansyah M, Dream S, . . . Kothari A. Socioeconomic Predictors of Mortality After Gastrectomy Differ in Aggregated Versus Disaggregated Asian Subpopulations. Society of Asian Academic Surgeons Annual Conference. New Orleans. September 2024. [Oral]

SenthilKumar G, Muthukumar A, Fong Z, Buss R, . . . Calata J. Why are International Students Underrepresented in US-MD Schools? Society of Asian Academic Surgeons Annual Conference. New Orleans. September 2024. [Oral]

Gehl C, Li B, Ramamurthi A, SenthilKumar G, . . . Kothari A. Cardiothoracic surgery patients carrying a causal atrial fibrillation gene variant (ZFHX3) are at increased risk of developing postoperative new-onset atrial fibrillation. Society of Asian Academic Surgeons Annual Conference. New Orleans. September 2024.

Gehl C, Pedersen L, SenthilKumar G, Watt G . . . Bergom C, Kerns S. Germline Genetic Risk Factors for Cardiac Toxicity in Childhood Cancer Survivors Exposed to Heart Radiotherapy: A Report from the Childhood Cancer Survivor Study (CCSS). Radiation Research Society. September 2024.

Shaik T, Yang X, Wolfrath N, SenthilKumar G, . . . Kothari A. Integrating a Machine Learning Model into Web-Based App to Predict Readmission After CRS+/- HIPEC. Society of Asian Academic Surgeons Annual Conference. New Orleans. September 2024.

SenthilKumar G, Jaramillo-Torres M, . . . Freed JK. Chronic Estrogen Treatment Promotes Human Microvascular Endothelial Dysfunction Through Sex-Specific Regulation of Ceramide Formation. Microcirculatory Society Annual Meeting 2023. April 2024. Trainee Flash Talks Session. [Oral]

SenthilKumar G, Jaramillo-Torres M, . . . Freed JK. Chronic Estrogen Treatment Promotes Human Microvascular Endothelial Dysfunction Through Sex-Specific Regulation of Ceramide Formation. American Physiology Summit 2024. Long Beach CA. April 2024. (1) [Poster]. (2) Cardiovascular Section Outstanding Graduate Student Trainee Award Competition [Oral]

Jaramillo-Torres M, SenthilKumar G, . . . Freed JK. Activation of Piezo1 Prevents Human Microvascular Endothelial Dysfunction During Acute Inhibition of Ceramide Formation. American Physiology Summit 2024. Long Beach CA. April 2024.

Torres Perez-Iglesias C, Mathew F, Cacao Coimbra B, SenthilKumar G, Raunak Goyal, Sidhu Gangadharan. Discrepancies in Perceptions of Essential Competencies for International Medical Graduates: A Comparative Study of Trainees and Faculty. Association of Surgical Education Annual Conference. April 2024.

Gehl C, Ramamurthi A, SenthilKumar G, . . . Kothari A. Variant in ZFHX3 Gene Increases Risk of Postoperative Atrial Fibrillation in Cardiothoracic Surgery. 19th Annual American Surgical Congress 2024. Annual Academic Surgical Congress. Washington DC. February 2024.

Shaik T, Yang X, Wolfrath N, SenthilKumar G, . . . Kothari A. Integrating a Machine Learning Model into Web-Based App to Predict Readdmission after CRS/HIPEC. 19th Annual American Surgical Congress 2024. Annual Academic Surgical Congress. Washington DC. February 2024.

SenthilKumar G, Zirgibel Z, . . . Freed JK. The Beneficial Effects of Ceramide on Human Microvascular Endothelial Function is Dependent on S1P/S1PR1 Signaling Axis. American Heart Association's Annual Meeting Scientific Sessions 2023. Chicago IL. November 2023. (1) ATVB Council's Early Career Reception [Invited Poster]. (2) Elaine W. Raines Early Career Investigator Award Competition. [Oral]

SenthilKumar G, Freed JK. The Necessary Role of Ceramide within the Human Microvascular Endothelium. American Heart Association's Annual Meeting Scientific Sessions 2023 Early Innovators Spotlight. Chicago IL. November 2023. [Oral]

Zirgibel Z, SenthilKumar G, . . . Freed JK. Role of Ceramide in Estrogen-Induced Oxidative Stress in Endothelial Cells from Individuals Assigned Male at Birth. American Heart Association’S Annual Meeting Scientific Sessions 2023. Chicago IL. November 2023. [Oral] by undergraduate mentee.

SenthilKumar G, Nathaniel B. Verhagen, Salma Sheriff ,. . . Kothari A. Risk Of Early Postoperative Cardiovascular Complications In Patients With Preoperative Covid-19 Undergoing Cancer Surgery. Scientific Forum at American College of Surgeons Clinical Congress 2023. October 2023. [Oral]

SenthilKumar G, Nathaniel B. Verhagen, Xin Yang, . . . Kothari A. Importance of Addressing Heterogeneity Among Asian Subgroups During Development of Machine Learning Models for Postoperative Risk Prediction. Society of Asian Academic Surgery Annual Meeting 2023. September 2023. [Plenary Oral]

Nathaniel B. Verhagen, SenthilKumar G, Carson Gehl, . . . Kothari A. From Alpha to Omicron and Beyond: Assessing the Impact of SARS-CoV-2 Variants on Surgical Outcomes. Society of Asian Academic Surgery Annual Meeting 2023. September 2023.

Carson Gehl, Nathaniel B. Verhagen, SenthilKumar G, . . . Kothari A. FitBit Sleep Data as a Tool for Surgical Risk Stratification. Society of Asian Academic Surgery Annual Meeting 2023. September 2023.

Sarah Y. Park, SenthilKumar G, Salma A. Sheriff, Aditya Shreenivas, . . . Anai N. Kothari. Heterogeneity in Stage IV Gastric Cancer Treatment and Outcomes Amongst Asian Subgroups. Society of Asian Academic Surgery Annual Meeting 2023. September 2023.

SenthilKumar G, Zirgibel Z, Lindemer B, . . . Freed JK. Activation of Piezo-1 Prevents Microvascular Endothelial Dysfunction During Acute Inhibition of Ceramide Formation. 38th Annual MD-PhD National Student Conference. July 2023. [Poster]

SenthilKumar G, Bordas-Murphy H, Lindemer B, Freed JK. Ceramide Signaling Potentiates Microvascular Endothelial Dysfunction In Patients With Coronary Artery Disease. Vascular Discovery: From Genes to Medicine 2023. May 2023. [Poster]

SenthilKumar G, Shult C, Bordas-Murphy H, Freed JK. Elevated Estrogen Induces Senescence in Male Endothelial Cells Via Neutral Sphingomyelinase-Mediated Ceramide Formation. 2023 American Physiology Summit. April 2023. [Oral]

Jaraczewski T, Thalji S, SenthilKumar G, Greer J, . . . Kothari A. Machine Learning Approach to Personalize Prediction of Recurrence Following Cytoreductive Surgery and HIPEC. Advanced Cancer Therapies 2023.

SenthilKumar G, Merrill J, Maduekwe U, Cloyd J, . . . Kothari A. Prediction Of Early Recurrence Following CRS/HIPEC in Patients with Appendiceal Cancer. 18th Annual Academic Surgical Congress. February 2023. [Oral]

Park S, SenthilKumar G, Sheriff S, Shreenivas A, . . . Kothari A. Heterogeneity in Stage IV Gastric Cancer Treatment and Outcomes Amongst Asian Subgroups. Society of Surgical Oncology 2023. March 2023.

SenthilKumar G, Katunaric B, Bordas-Murphy H, Freed JK. Exogenous Sphingosine-1-Phosphate Restores Nitric Oxide-Mediated Flow-Induced Dilation During Acute Inhibition of Ceramide Formation. American Heart Association's Annual Meeting Scientific Sessions 2022. November 2022. [Oral]

SenthilKumar G, Schottstaedt A, Stolley M, Chitambar C, . . . Bergom C. Comprehensive Diet and Exercise Intervention During Radiation Therapy Can Improve Metabolic and Inflammatory Markers in Breast Cancer Patients. American Heart Association's Annual Meeting Scientific Sessions 2022. November 2022. [Poster]

SenthilKumar G, Cloyd J, Fournier K, Abbott D, . . . Mogal H, Kothari A. Feasibility of Using Automated Machine Learning to Predict Exceptional Survivors in Well-differentiated Appendiceal Cancer Undergoing CRS/HIPEC. Society of Asian Academic Surgeons Annual Meeting 2022. September 2022. [Oral]

SenthilKumar G, Katunaric B, Bordas-Murphy H, Schulz M, Freed JK. Sphingosine-1-Phosphate Signaling in the Human Microvascular Endothelium During Health and Disease. American Heart Association Vascular Discovery: From Genes to Medicine 2022. May 2022. [Poster]

SenthilKumar G, Koerber N, Merrill J, Clarke CN, . . Kothari A. Feasibility of Automatic Machine Learning (AutoML) to Predict 90-Day Mortality after Gastrectomy for Cancer. Digestive Disease Week 2022. May 2022. [Oral]

SenthilKumar G, Katunaric B, Bordas-Murphy H, Young M, Buiter N, Freed JK. Is Estrogen a Friend or Foe of the Human Microcirculation throughout the Lifespan? Experimental Biology. April 2022. [Oral]

SenthilKumar G, Heisner J, Schlaak R, Mishra J, Katunaric B, Camara A, Bergom C. What Doesn’t Kill You Makes You Stronger - Even Heart Radiation? Experimental Biology. April 2022. [Poster]

Katunaric B, SenthilKumar G, Schulz M, Freed JK. Role of NOX2 in Ceramide-Induced Human Microvascular Endothelial Dysfunction. Experimental Biology. April 2022.

SenthilKumar G, Cole KE, Ellinas E. Why are women underrepresented in healthcare leadership? Center for the Advancement of Women in Science and Medicine Symposium, Medical College of Wisconsin, Milwaukee, WI, USA. March 2022. Virtual. [Poster, AWSM Symposium Education Session Winner]

Cole KE, SenthilKumar G, Treat R, Farkas A, Ellinas E. Designing a Self-Directed, Online Module to Promote Student Leadership and Intentional Involvement. Innovations in Medical Education Online Conference, Keck School of Medicine of University of Southern California, CA, USA. February 2022. Virtual. [Poster]

SenthilKumar G, Cole KE, He Y, Stark K, Craig T, Meurer J. Student Leadership Development Initiative: A Model for Training Medical Students Around the World. Innovations in Medical Education Online Conference, Keck School of Medicine of University of Southern California, CA, USA. February 2022. Virtual. [Poster]

Cole K* & SenthilKumar G*. Designing a leadership curriculum for medical students that teaches students to be influencers. Innovations in Healthcare Education Research Conference, Medical College of Wisconsin, Milwaukee, WI, USA. September 2021. Virtual. [Poster]

Senthilkumar G, Cole, KE, Fritz JD. Does Emotional Intelligence Matter for Medical Professionals? How Can We Foster It? AAMC 2021 GSA-OSR Spring Meeting. April 2021. [Oral Poster]

Senthilkumar G, Rokkas CK, Linsky PL. A functional, subcarinal paraganglioma adherent to the left atrial wall and supplied by large branches of the coronary and bronchial arteries. American College of Physicians Wisconsin Chapter. September 2020. [Poster]. American College of Physicians National Abstract Competition Winner. May 2020. [Oral]

Senthilkumar G, Gamblin TC, Clarke CN, Kimbrough C, et al. Characteristics of Exceptional vs Poor survivors in Colorectal Cancer Patients undergoing Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy. Society of Surgical Oncology 2021 Annual Meeting. March 2021. [Oral Poster]

Senthilkumar G, Thalji SZ, Clarke CN, Kimbrough C, et al. Characteristics and Outcomes of Exceptional vs Poor survivors in Disseminated Appendiceal Cancer Patients undergoing CRS/HIPEC – A Multi-institutional Analysis. Wisconsin Surgical Society 2020 Annual Meeting. November 2020. [Oral Presentation]. 16th Annual Academic Surgical Congress. February 2021. [Quickshot Oral]

Jaraczewski T, Thalji S, SenthilKumar G, Clarke CN, Gamblin T, Maduekwe U, Kothari A. Application of Machine Learning to Determine United States County-Level Health Predictors of Disparities in Gastrointestinal Cancer Mortality Trends. Society of Surgical Oncology 2022 Annual Meeting. February 2021.

Senthilkumar G, Fernando D, Gamblin TC, et al. Validation of the AJCC 8th Edition Staging System for Appendiceal Cancer Using a Multi-institutional Cohort of Patients Treated with Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy (CRS/HIPEC). American College of Surgeons Clinical Congress 2020. October 2020. [Oral Presentation]

Fernando D, Senthilkumar G, Clarke CN, et al. Role of Cytoreduction and Hyperthermic Intraperitoneal Chemotherapy (CRS/HIPEC) in the treatment of Peritoneal Carcinomatosis from Small Bowel Adenocarcinoma: A Systematic Review. American College of Surgeons Clinical Congress 2020. October 2020. [Poster]

Lee YS, Skiba J, Senthilkumar G, et al. Inhibition of radiation-induced autophagy improves control of head and neck squamous cell carcinoma. International Journal of Radiation Oncology Biology Physics. March 2020. Abstract 323. [Poster]

Senthilkumar G, Miller M, Fisher MM, et al. Radiosensitization of head and neck cancer by FGFR inhibition. American Association of Cancer Research 2019 Proceedings. Abstract 2929. April 2019. [Poster]

Miller M, Fisher MM, Senthilkumar G, et al. Evaluation of the pan-FGFR inhibitor AZD4547 with radiation in non-small cell lung cancer. American Association of Cancer Research 2019 Proceedings. Abstract 2924. April 2019. [Poster]

Eckers J, Skiba J, Senthilkumar G, et al. Autophagy contributed to therapeutic resistance in head and neck cancer. American Association of Cancer Research 2018 Proceedings. Abstract 1344. [Poster]

General Interests

Running, swimming, drawing/painting, boxing, trying new local restaurants