Matthew Hadiono
M3 Student
Faculty Advisor
- John Kirby, PhD, Microbiology & Immunology
Locations
- Medical Scientist Training Program
Contact Information
Education
Research Interests
Gut microbiome and human disease, cellular immunology, use of organoids as an experimental model
Research Experience
Medical College of Wisconsin, 2019-2024
Advisor: John Kirby, PhD
Project: Modulation of gut microbial metabolism and energy expenditure by xenobiotics and bacterial metabolites
Case Western Reserve University, Comprehensive Cancer Center, 2015-2016
Advisor: Dr. Sanford Markowitz
Project: Investigated the therapeutic potential of a novel small enzyme inhibitor of 15-PGDH (SW033291) in a DSS-colitis mouse model
Case Western Reserve University, Biomedical Research Building, 2013-2015
Advisor: Dr. Daniel Popkin
Project: Investigated the role of dendritic cells in persistent viral infection (LCMV, mouse model). Investigated the role of plasmacytoid dendritic cells in the initiation of psoriasis (imiquimod mouse model)
Publications
Lozada-Fernández VV, deLeon O, Kellogg SL, Saravia FL, Hadiono MA, Atkinson SN, Grobe JL, Kirby JR. Nicotinamide Riboside-Conditioned Microbiota Deflects High-Fat Diet-Induced Weight Gain in Mice. mSystems. 2022 Feb 22;7(1):e0023021. doi: 10.1128/msystems.00230-21. Epub 2022 Jan 25. PMID: 35076278; PMCID: PMC8788325.
Griffith AD, Zaidi AK, Pietro A, Hadiono M, Yang JS, Davis R, Popkin DL. A requirement for slc15a4 in imiquimod-induced systemic inflammation and psoriasiform inflammation in mice. Sci Rep. 2018;8(1):14451. Published 2018 Sep 27. doi:10.1038/s41598-018-32668-9
General Interests
Piano and guitar (all genres), climbing, cooking, and finding great hiking/camping spots around Wisconsin