Ophthalmology Grand Rounds

Clinical Applications of High-Resolution Retinal Imaging

Presenter:
Dr. Joseph Carroll

The human retina is an easily accessible tissue and can be non-invasively imaged using a number of different modalities. The ability to directly visualize the living retina provides an implicit advantage in diagnosing and monitoring retinal disease. While OCT enables resolution of different retinal layers and OCT-angiography allows visualization of the retinal vasculature, adaptive optics based imaging systems have superior lateral resolution and are capable of imaging the smallest photoreceptor cells in the living retina. The clinical application of such images is fundamentally limited by the ability to extract quantitative information from them. In this talk Dr. Carroll will review how we have applied retinal imaging to better understand treatment potential in achromatopsia and structure-function relationships in albinism. He will also review our efforts in analyzing various types of retinal images and will discuss limitations regarding the derivation of quantitative metrics.