Jason W. Sidabras, PhD

Assistant Professor

Locations

Biophysics
MFRC 2058

Contact Information

General Interests

Protein structure/function, technology development for magnetic resonance, MRI coil development; EPR instrumentation development

Education

PhD (Doctor rerum naturalium), Physics, Technical University Dortmund, Dortmund, Germany, 2020
MS, Electrical Engineering, Marquette University, 2010
BS, Electrical Engineering Technology, Milwaukee School of Engineering, Milwaukee, WI, 2003

Biography

I earned a BS in electrical engineering technology from the Milwaukee School of Engineering and an MS in electrical engineering from Marquette University. While pursuing these degrees, I worked as a research engineer in the MCW Department of Biophysics. I then relocated to Germany, where I conducted my doctoral dissertation research at the Max Planck Institute for Chemical Energy Conversion and defended my dissertation at the Technical University of Dortmund. I received a Dr. rer. nat. (PhD equivalent) in physics in January 2020. In late 2020, I returned to the MCW Department of Biophysics as an assistant professor.

                
                    Research Areas of Interest
                
                    Computer Simulation
Computer-Aided Design
Electromagnetic Fields
Electron Spin Resonance Spectroscopy
Equipment Design
Finite Element Analysis
Microwaves
Signal Processing, Computer-Assisted

                    Research Experience
                
                    Biophysics
Computer Simulation
Electromagnetic Fields
Electromagnetic Phenomena
Electron Spin Resonance Spectroscopy
Finite Element Analysis
Microwaves
Physics

                    Methodologies and Techniques
                
                    Electron Spin Resonance Spectroscopy
Magnetic Resonance Imaging
Magnetic Resonance Spectroscopy

Research Interests

My research interests currently focus on technology development to improve magnetic resonance experiments. Applications of the technology range from instrumentation development for electron paramagnetic resonance (EPR) for studying protein structure, function, and dynamics to coil development for human and small mammal functional MRI.

Lab Members
Anand Anilkumar, Graduate Student
Richard Scherr, Engineering Technician III
Akansha Sharma, PhD, Postdoctoral Fellow
Joseph Wehrley, Engineering Technician I

A pressure-jump EPR system to monitor millisecond conformational exchange rates of spin-labeled proteins.

(Grosskopf JD, Sidabras JW, Altenbach C, Anderson JR, Mett RR, Strangeway RA, Hyde JS, Hubbell WL, Lerch MT.) bioRxiv. 2024 May 11 PMID: 38766191 PMCID: PMC11100676 05/20/2024
Benefits and challenges of in vivo EPR nail biodosimetry in a second tier of medical triage in response to a large radiation event.

(Flood AB, Sidabras JW, Swarts SG, Buehler PW, Schreiber W, Grinberg O, Swartz HM.) Radiat Prot Dosimetry. 2023 Sep 18;199(14):1539-1550 PMID: 37721065 PMCID: PMC10505939 09/18/2023
A personal account on 25 years of scientific literature on [FeFe]-hydrogenase.

(Sidabras JW, Stripp ST.) J Biol Inorg Chem. 2023 Jun;28(4):355-378 PMID: 36856864 03/02/2023
Milliwatt three- and four-pulse double electron electron resonance for protein structure determination.

(Teucher M, Sidabras JW, Schnegg A.) Phys Chem Chem Phys. 2022 May 25;24(20):12528-12540 PMID: 35579184 05/18/2022
Dispersion EPR: Considerations for Low-Frequency Experiments.

(Hyde JS, Strangeway RA, Sidabras JW.) Appl Magn Reson. 2022 Jan;53(1):193-206 PMID: 35464635 PMCID: PMC9030583 04/26/2022
Resonators for Multifrequency EPR of Spin Labels

(Hyde JS, Sidabras JW, and Mett RR.) Multifrequency Electron Paramagnetic Resonance: Theory and Applications, Chapter 5.2, Edited By Sushil K. Misra. John Wiley & Sons 12/08/2020
Dielectric-Backed Aperture Resonators for X-band Depth-Limited in Vivo EPR Nail Dosimetry.

(Grinberg O, Sidabras JW, Tipikin D, Krymov V, Swarts SG, and Swartz HM .) Appl. Magn. Reson.,51, 1093–1101 (2020). 09/20/2020
Extending electron paramagnetic resonance to nanoliter volume protein single crystals using a self-resonant microhelix.

(Sidabras JW, Duan J, Winkler M, Happe T, Hussein R, Zouni A, Suter D, Schnegg A, Lubitz W, Reijerse EJ.) Sci Adv. 2019 Oct;5(10):eaay1394 PMID: 31620561 PMCID: PMC6777973 10/18/2019
Rutile dielectric loop-gap resonator for X-band EPR spectroscopy of small aqueous samples.

(Mett RR, Sidabras JW, Anderson JR, Klug CS, Hyde JS.) J Magn Reson. 2019 Oct;307:106585 PMID: 31499469 PMCID: PMC6948142 SCOPUS ID: 2-s2.0-85071859156 09/10/2019
Photobleaching of pheomelanin increases its phototoxic potential: Physicochemical studies of synthetic pheomelanin subjected to aerobic photolysis.

(Zadlo A, Szewczyk G, Sarna M, Camenisch TG, Sidabras JW, Ito S, Wakamatsu K, Sagan F, Mitoraj M, Sarna T.) Pigment Cell Melanoma Res. 2019 May;32(3):359-372 PMID: 30457208 11/21/2018
Uniform Field Resonators for EPR Spectroscopy: A Review.

(Hyde JS, Sidabras JW, Mett RR.) Cell Biochem Biophys. 2019 Mar;77(1):3-14 PMID: 29943362 PMCID: PMC6309773 SCOPUS ID: 2-s2.0-85049038251 06/27/2018
Developments in Biodosimetry Methods for Triage With a Focus on X-band Electron Paramagnetic Resonance In Vivo Fingernail Dosimetry.

(Swarts SG, Sidabras JW, Grinberg O, Tipikin DS, Kmiec MM, Petryakov SV, Schreiber W, Wood VA, Williams BB, Flood AB, Swartz HM.) Health Phys. 2018 Jul;115(1):140-150 PMID: 29787440 PMCID: PMC5967651 05/23/2018

Jason W. Sidabras, PhD

Assistant Professor

Locations

Contact Information

General Interests

Education

Biography

Research Areas of Interest

Research Experience

Methodologies and Techniques

Research Interests

Publications