Linda Olson, PhD

Publications

• Structure-Based Lead Optimization of Enterovirus D68 2A Protease Inhibitors.

  (Tan B, Liu C, Li K, Jadhav P, Lambrinidis G, Zhu L, Olson L, Tan H, Wen Y, Kolocouris A, Liu W, Wang J.) J Med Chem. 2023 Nov 09;66(21):14544-14563 PMID: 37857371 PMCID: PMC11457037 SCOPUS ID: 2-s2.0-85176509223 10/20/2023

• Tissue plasminogen activator is a ligand of cation-independent mannose 6-phosphate receptor and consists of glycoforms that contain mannose 6-phosphate.

  (Miller JJ, Bohnsack RN, Olson LJ, Ishihara M, Aoki K, Tiemeyer M, Dahms NM.) Sci Rep. 2021 Apr 15;11(1):8213 PMID: 33859256 PMCID: PMC8050316 SCOPUS ID: 2-s2.0-85104287178 04/17/2021

• Allosteric regulation of lysosomal enzyme recognition by the cation-independent mannose 6-phosphate receptor.

  (Olson LJ, Misra SK, Ishihara M, Battaile KP, Grant OC, Sood A, Woods RJ, Kim JP, Tiemeyer M, Ren G, Sharp JS, Dahms NM.) Commun Biol. 2020 Sep 09;3(1):498 PMID: 32908216 PMCID: PMC7481795 SCOPUS ID: 2-s2.0-85090384984 09/11/2020

• Cloning, Expression, and Purification of the Glycosylated Transmembrane Protein, Cation-Dependent Mannose 6-Phosphate Receptor, from Sf9 Cells Using the Baculovirus System.

  (Olson LJ, Dahms NM.) Methods Mol Biol. 2018;1722:105-116 PMID: 29264801 PMCID: PMC6202031 SCOPUS ID: 2-s2.0-85038831305 12/22/2017

• Crystal Structure and Functional Analyses of the Lectin Domain of Glucosidase II: Insights into Oligomannose Recognition.

  (Olson LJ, Orsi R, Peterson FC, Parodi AJ, Kim JJ, D'Alessio C, Dahms NM.) Biochemistry. 2015 Jul 07;54(26):4097-111 PMID: 26062005 PMCID: PMC6202027 SCOPUS ID: 2-s2.0-84936769044 06/11/2015

• Bacterial expression of the phosphodiester-binding site of the cation-independent mannose 6-phosphate receptor for crystallographic and NMR studies.

  (Olson LJ, Jensen DR, Volkman BF, Kim JJ, Peterson FC, Gundry RL, Dahms NM.) Protein Expr Purif. 2015 Jul;111:91-7 PMID: 25863146 PMCID: PMC4417374 SCOPUS ID: 2-s2.0-84927727743 04/12/2015

• Identification of a fourth mannose 6-phosphate binding site in the cation-independent mannose 6-phosphate receptor.

  (Olson LJ, Castonguay AC, Lasanajak Y, Peterson FC, Cummings RD, Smith DF, Dahms NM.) Glycobiology. 2015 Jun;25(6):591-606 PMID: 25573276 PMCID: PMC4410830 SCOPUS ID: 2-s2.0-84930944628 01/13/2015

• Mannose 6-Phosphate Receptors

  (Olson LJ, Dahms NM.) Glycoscience: Biology and Medicine. 1 January 2015:1037-1048 SCOPUS ID: 2-s2.0-84943616477 01/01/2015

• Structure of the lectin mannose 6-phosphate receptor homology (MRH) domain of glucosidase II, an enzyme that regulates glycoprotein folding quality control in the endoplasmic reticulum.

  (Olson LJ, Orsi R, Alculumbre SG, Peterson FC, Stigliano ID, Parodi AJ, D'Alessio C, Dahms NM.) J Biol Chem. 2013 Jun 07;288(23):16460-16475 PMID: 23609449 PMCID: PMC3675582 SCOPUS ID: 2-s2.0-84878756888 04/24/2013

• The glycan-binding properties of the cation-independent mannose 6-phosphate receptor are evolutionary conserved in vertebrates.

  (Castonguay AC, Lasanajak Y, Song X, Olson LJ, Cummings RD, Smith DF, Dahms NM.) Glycobiology. 2012 Jul;22(7):983-96 PMID: 22369936 PMCID: PMC3355666 SCOPUS ID: 2-s2.0-84861409583 03/01/2012

• Mannose 6-phosphate receptor homology (MRH) domain-containing lectins in the secretory pathway.

  (Castonguay AC, Olson LJ, Dahms NM.) Biochim Biophys Acta. 2011 Sep;1810(9):815-26 PMID: 21723917 PMCID: PMC3150748 SCOPUS ID: 2-s2.0-79960702536 07/05/2011

• Structural basis for recognition of phosphodiester-containing lysosomal enzymes by the cation-independent mannose 6-phosphate receptor.

  (Olson LJ, Peterson FC, Castonguay A, Bohnsack RN, Kudo M, Gotschall RR, Canfield WM, Volkman BF, Dahms NM.) Proc Natl Acad Sci U S A. 2010 Jul 13;107(28):12493-8 PMID: 20615935 PMCID: PMC2906551 SCOPUS ID: 2-s2.0-77955444897 07/10/2010