Radiation Oncology Clinical Research at the Medical College of Wisconsin

The pursuit and discovery of basic, translational, clinical, medical physics, and radiobiological knowledge that advances the field and practice of radiation oncology is fundamental to all missions. Our departmental research efforts remain focused on clinical and translational physics research related to our original work in image guided and online adaptive radiation therapy. A new departmental focus is the use of radiogenomics, delta-radiomics, and molecular phenotyping to develop normal tissue and tumor response biomarkers linked where possible to imaging biomarkers of tumor and normal tissue response, respectively. Our long-standing interest and expertise in mitigation of normal tissue radiation injury will continue to be relevant and complimentary to this new focus. The recent launch of the of the Radiation Oncology Committee to Advance Knowledge and Education through Clinical Trials or “ROCKET” clinical trial framework provides a pathway to move radiation oncology discovery into multidisciplinary clinical practice.